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Thursday, 30 March 2023

Darwin vs. Darwinism?

 Darwin’s Top 10 Arguments Against His Own Theory


In a recent article Here I referred to my canceled presentation at the annual conference of the National Science Teaching Association. My topic was to be, “The Top 10 Scientific Arguments Against Darwin’s Theory — According to Darwin Himself.” What are those top ten arguments? Let’s take a look.

Charles Darwin took seriously objections to his theory that had been raised by many of the most eminent naturalists of his day. In The Origin of Species he considered in detail 37 of them. Darwin acknowledged that there were “a crowd of difficulties” with his theory and stated, “Some of them are so serious that to this day I can hardly reflect on them without being in some degree staggered; but, to the best of my judgment, the greater number are only apparent, and those that are real are not, I think, fatal to the theory.” (p. 158) (All citations are to Charles Darwin, The Origin of Species (New York: NAL Penguin Inc., 1958).)

Based on Darwin’s discussion in The Origin of Species, it is reasonable to conclude that he considered the arguments set forth below to be the top ten scientific arguments against his theory. These arguments relate to Darwin’s proposed mechanism for evolution, i.e., the application of natural selection to randomly produced variations. (Note: With respect to the origin of life, Darwin theorized in The Origin of Species that the very first forms of life (at most, eight to ten forms) were produced by the Creator. He did not consider any arguments against this part of his theory and apparently none were raised by the naturalists of his day, most of whom subscribed to a theory of design.)

Darwin’s thoughtful consideration of the scientific arguments against his theory is consistent with his hope for the future: “I look with confidence to the future, — to young and rising naturalists, who will be able to view both sides of the question with impartiality.” (p. 444)
                
1. The Complexity of Eyes

Darwin states, “To suppose that the eye with all its inimitable contrivances for adjusting the focus to different distances, for admitting different amounts of light, and for the correction of spherical and chromatic aberration, could have been formed by natural selection, seems, I freely confess, absurd in the highest degree.” (p. 168) 

2. Existence of Similar Organs in Remotely Allied Species

Darwin considers the electric organs of species of fish that are remotely allied and also the luminous organs of insects “belonging to widely different families.” He states that the latter “offer, under our present state of ignorance, a difficulty almost exactly parallel with that of the electric organs.” (p. 176)

Darwin admits the difficulty under his theory “of an organ, apparently the same, arising in several remotely allied species.” (p. 176)

3.Existence of Different Organs for the Same Function in Closely Allied Species

Darwin considers two genera of orchid, the Coryanthes and the Catasetum. He explains in detail the ingenious “contrivance” that the Coryanthes uses for pollination. He then turns to the Catasetum, which is “closely allied” to the Coryanthes, and states that the construction of the flower in the Catasetum “is widely different, though serving the same end.” (p. 180)

Darwin admits that it is common throughout nature for the same end to be gained by the most diversified means, “even sometimes in the case of closely-related beings.” (p. 178) 

4. Parts with Little Importance

Darwin states, “I have sometimes felt great difficulty in understanding the origin or formation of parts of little importance; almost as great, though of a very different kind, as in the case of the most perfect and complex organs.” (p. 181) He mentions the tail of the giraffe as an example of a part with little apparent importance. He states that it looks like “an artificially constructed fly-flapper” and “[it] seems at first incredible that this could have been adapted for its present purpose by successive slight modifications, each better and better fitted, for so trifling an object as to drive away flies.” (p. 181)

5. Complex Instincts

Darwin acknowledges, “Many instincts are so wonderful that their development will probably appear to the reader a difficulty sufficient to overthrow my whole theory.” (p. 228)

Darwin states, “He must be a dull man who can examine the exquisite structure of a [honeycomb], so beautifully adapted to its end, without enthusiastic admiration. We hear from mathematicians that bees have practically solved a recondite problem, and have made their cells of the proper shape to hold the greatest possible amount of honey, with the least possible consumption of precious wax in their construction. It has been remarked that a skilful workman … would find it very difficult to make cells of wax of the true form, though this is effected by a crowd of bees working in a dark hive.” (pp. 242-243)

6. Neuter Ants and Their Different Castes

With respect to neuter ants, Darwin states it is “one special difficulty, which at first appeared to me insuperable, and actually fatal to the whole theory … for these neuters often differ widely in instinct and in structure from both the males and fertile females, … yet, from being sterile, they cannot propagate their kind.” (p. 250)

Darwin goes on to state, “But we have not as yet touched on the acme of the difficulty; namely, the fact that the neuters of several ants differ, not only from the fertile females and males, but from each other, sometimes to an almost incredible degree, and are thus divided into two or even three castes.” (p. 253) He acknowledges, “It will indeed be thought that I have an overweening confidence in the principle of natural selection, when I do not admit that such wonderful and well-established facts at once annihilate the theory.” (p. 253)

7. The Eyes of the Flat-Fish

During its early youth the body of the flat-fish is symmetrical with one eye on each side. However, as the body matures, one eye “begins to glide slowly round the head” to the other side. (pp. 209-210) This is beneficial because the adult flat-fish spends most of its time lying on its side on the bottom of the ocean. 

Darwin agrees that his theory of natural selection cannot account for this feature. He states that it “may be attributed to the habit, no doubt beneficial to the individual and to the species, of endeavouring to look upwards with both eyes, whilst resting on one side at the bottom.” (p. 211) Thus, it “may be attributed almost wholly to continued use, together with inheritance.” (pp. 222-223)

8. Absence of Transitional Forms in the Fossil Record

With respect to the absence of transitional forms in the fossil record, Darwin states that under his theory, “…as this process of extermination has acted on an enormous scale, so must the number of intermediate varieties, which have formerly existed, be truly enormous. Why then is not every geological formation and every stratum full of such intermediate links? Geology assuredly does not reveal any such finely-graduated organic chain; and this, perhaps, is the most obvious and serious objection which can be urged against the theory.” (p. 287) Darwin admits that “though we do find many links — we do not find interminable varieties, connecting together all extinct and existing forms by the finest graduated steps.” (pp. 335-336) 

He states, “That the geological record is imperfect all will admit; but that it is imperfect to the degree required by our theory, few will be inclined to admit.” (p. 431) He also acknowledges, “He who rejects this view of the imperfection of the geological record, will rightly reject the whole theory.” (p. 336)

9. Absence of Transitional Forms Even Within Particular Geological Formations

With respect to the absence of transitional forms even within particular geological formations, Darwin states, “[I]t cannot be doubted that the geological record, viewed as a whole, is extremely imperfect; but if we confine our attention to any one formation, it becomes much more difficult to understand why we do not therein find closely graduated varieties between the allied species which lived at its commencement and at its close.” (p. 298)

He confesses, “But I do not pretend that I should ever have suspected how poor was the record in the best preserved geological sections, had not the absence of innumerable transitional links between the species which lived at the commencement and close of each formation, pressed so hardly on my theory.” (pp. 304-305)

10. Sudden Appearance of New Forms of Life

Darwin states, “The abrupt manner in which whole groups of species suddenly appear in certain formations, has been urged by several paleontologists — for instance, by Agassiz, Pictet, and Sedgwick — as a fatal objection to the belief in the transmutation of species.” (p. 305) 

He goes on to state, “There is another and allied difficulty, which is much more serious. I allude to the manner in which species belonging to several of the main divisions of the animal kingdom suddenly appear in the lowest known fossiliferous rocks,” i.e., the Cambrian strata. (p. 308) “To the question why we do not find rich fossiliferous deposits … prior to the Cambrian system, I can give no satisfactory answer.” (p. 309) Darwin concludes, “The case at present must remain inexplicable; and may be truly urged as a valid argument against the views here entertained.” (p. 310)


Wednesday, 29 March 2023

File under "well said." XCIV

 "he fondly imagined people to be intelligent enough to accept a good thing when it was offered to them, which was conclusive evidence that he knew little about the human race."

George Schuyler

The other Wilberforce?

 Robert Shedinger: Darwin’s Sacred Cause Is “Historical Fiction”


On a new episode of ID the Future, science-and-religion scholar Robert Shedinger makes the case that a well-known historical work about Charles Darwin, Darwin’s Sacred Cause, is deeply misleading. The book by Adrian Desmond and James Moore holds that Darwin was significantly motivated in his scientific work by abolitionist sentiments; and Shedinger says, not so fast. He had spent considerable time reading Darwin’s correspondence and had seen no evidence supporting this thesis, so he reread Darwin’s Sacred Cause, this time tracking down all the key citations the book offered as evidence, and a pattern soon emerged. The sources the authors cite didn’t actually support their thesis. Some were totally irrelevant. Some were cited completely out of context. In other cases, the authors gave the impression that Darwin said something when the comment they attributed to him was stitched together from multiple correspondences and the constituent comments were often about something else altogether. Shedinger says he realized that this biography that looked to be so well documented amounted to “historical fiction.” The effect of the book is to misrepresent Darwin in such a way as to make those who reject Darwinism appear to be opposing a saintly anti-abolitionist.

While Darwin did hold anti-slavery sentiments, they didn’t drive his science and he himself was anything but free from racism. In fact, his case for human evolution partly rested on deeply demeaning racist attitudes toward indigenous peoples. For more on this, see historian Richard Weikart’s book Darwinian Racism.

Also in this episode, Shedinger tells host Michael Keas about how he went from a scholar fully persuaded of Darwinian theory to a skeptic of modern evolutionary theory, attracted to the theory of intelligent design. Shedinger lays out his case against Darwinism in his recent Book The Mystery of Evolutionary Mechanisms. Download the podcast or listen to it Here

Yet another clash of titans.

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Copying the original engineer?

 Engineering Brings Life and Vice Versa


I came across an uplifting video about a life-saving invention that encapsulates several running themes about intelligent design. If you can, take 22 minutes to watch this video by Mark Rober, a former NASA engineer. I assure you it will be well worth your time.

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The story is uplifting on many levels. How wonderful is it to see former enemies from a major genocide in 1994 having learned how to live together in peace 30 years later? How inspiring is it to see one near victim of that slaughter starting in poverty to become a Harvard engineer and inventor in a company that is saving lives? How beautiful is it to see smiling children mastering soccer with a makeshift ball? How gratifying to prove naysayers wrong, and to show the fruit of well-tested engineering being put to beneficial use in the poorest parts of the world? I was very impressed by this story.

There was one brief statement I will criticize, but otherwise this video made my day, especially since I have relatives in Africa on a medical mission who may soon benefit from this amazing technology. Whether or not you like drones or believe this type of delivery system will change shopping in America (I can see lawyers rubbing their hands), the way the invention is working in Africa right now cannot help but impress. This is the power of ethical intelligent design in action. Let’s look at some lessons from this story.
           
Biomimetics

The heroes of the story are the birds. They were already masters of takeoff, landing, and pinpoint navigation. An owl was the inspiration for the Zipline drone’s whisper-quiet propeller system. A hummingbird inspired their miniaturized and silent flight control. As I like to say, if the engineers can get their drones to lay eggs and hatch babies with the software and hardware already included, that can grow larger while maintaining function, and power themselves from the environment by ingesting worms, they will really have something to brag about. Bravo to the birds that once again inspired inventors from the Wright Brothers to the high-tech engineers of NASA and Zipline.
                    
Trial and Error with Thinking
                 As Rober shows, Abdul and his crew had to try and fail many times. They succeeded through the failures and made progress because they applied their minds to problem solving. By thinking, and learning the principles of how things work, elucidated by great minds of the past, they could bring parts together to achieve a goal that first existed only in the mind’s eye. They could envision a concept, experiment, and test possibilities, making progress toward the goal by learning from their failures. 

Darwinians tell us that is how natural selection works, but think about it. (In passing, note that thinking also requires a mind.) If nature is mindless and aimless, with no foresight, could it invent a Zipline delivery system, much less a bird as they claim happened? A fundamental ID principle first clearly enunciated by Michael Behe is that irreducibly complex systems defeat the Darwinian mechanism and give positive evidence for intelligent design. We see that in this story implicitly.

Altruistic Design

Another thing the Darwinians continue to teach (examples here and here) is that altruism evolved by natural selection. Indeed, they attribute every noble ideal in human society to this blind, aimless, purposeless “mechanism” that works in bacteria similarly to how (they say) it works in human societies. With their evolutionary game theory models, they divide up members of a population into cooperators and cheaters whose actions are genetically determined by the mechanism, not by morality or by human exceptionalism. But doesn’t this quote from the video knock the air out of that explanation? Rober shows battle scars from the Rwandan genocide, then says,
                 As horrific as that ways, it galvanized the country to a period of healing and solidarity as a single Rwandan people instead of divisive ethnic groups. For instance, on the last Saturday of the month, literally everyone spends the day picking up trash and volunteering in their local communities. And that’s one of the reasons you hardly see litter anywhere…. There was just a pervasive optimism everywhere. Everyone was moving with a purpose everywhere we went, not just working hard, but working smart with the resources on hand…

For over a decade, attending school up to age 16 has been both mandatory and free. And when you combine that with leapfrogging to new technologies like drone delivery, in the last decade their economy has been growing at four times the rate of the U.S. economy, while their violent crime rate has been 15 times less than the U.S.
                         Who can say with a straight face that these Rwandan people, recovering from a devastating civil war, are just pawns of evolutionary game theory? Who can say that Abdul, after his near escape from terror that took his family, is no better than a germ cooperating with other bacteria? To even suggest such a notion is to defeat it. That word purpose stands out as anti-Darwinian as anything in the whole video. 

This calls for an occasion to promote the new Book Darwin Comes to Africa by Olufemi Oluniyi, who recounts the abominations wrought by the European imperialists who were mostly ardent believers in Social Darwinism. Would Darwinists today draw no distinctions between the altruistic, cooperative black Africans of Rwanda, whose behavior serves as a model for Westerners, than the colony of gorillas Mark Rober visited next in the video? Perish the racist thought. Westerners could learn some lessons from the morals of these friendly people who turned evil into good, and from Abdul whose noble soul did not take the evolutionary route of retaliation for his own personal fitness but instead is today saving the lives of distant people he hasn’t even met.
              
Teaching Design
             Rober bypasses academia at one point. He shares his vision of getting children to build things and learn by doing, realizing that “thinking like an engineer” means breaking things to figure out what works and what doesn’t. How many of the happy children he shows trying to solve simple problems, like getting a ping pong ball to bounce into a boot, will be likely to end up Darwinists? The harder the problem, the more the student will learn that things don’t just happen. Teaching engineering at an early age may prove to be the antidote to Darwinism for the next generation
          
The Flaw

OK, so what is the lone criticism I have of the video? It’s a throwaway line when Rober claims that “with owls, there’s an evolutionary pressure to be as quiet as possible” as he shows an owl flying imperceptibly past a line of microphones. What can possibly be meant by “evolutionary pressure”? The Darwinist imagines that adaptations are caused by an organism’s surroundings. The Darwinist believes that innovations that are engineering marvels, like powered flight, can emerge this way. For those who maintain that environments have such power, consider a simple illustration. The desert pupfish in Nevada have faced environmental pressure from increasing salinity as their habitats dry up, and now survive high salt concentrations that would kill other fish. Isn’t that “evolutionary pressure” forcing them to adapt? There are several problems with this explanation. 

For one thing, a chance mutation that helps a lone pupfish survive increasing salt is not going to aid the individual, but only its offspring. Standard neo-Darwinism teaches that the beneficial mutation needs to occur in the germline, not in somatic cells. Even if epigenetic benefits can be inherited, as has been shown more recently, they cannot happen gradually by random mutations, but involve rewiring of complex genetic circuits. Second, the neo-Darwinian explanation transfers the cause of adaptation to the environment instead of locating it in the organism. This borders on vitalism or personification, as if the environment is pressuring the organism in certain adaptive directions. The environment is mindless; it cannot care what happens. Extinction is a perfectly valid option, as the fossil record shows. Third and most important, the pupfish can only adapt if there is built-in engineering for adaptation prior to need. This presupposes an ability to sense the change, reprogram itself, and alter its own responses. Intelligent design for robustness in changing environments matches what engineers do when they build in redundancy and fail-safe mechanisms, as shown in the video. The owl that flies silently was not “pressured” by “evolution” to adapt its wing feathers. The cause of the adaptation was internal to the owl. That required foresight, not a randomly changing environment. 

Enough on that minor flaw in the video. Everything else was spectacularly encouraging for ID advocates. By the way, signups are being taken for the next CELS event (Conference on Engineering in Living Systems) in Texas this June 3-10. Read about it here.
                    
The Uplift
                    For an upbeat summary, Rober’s ending comment bears repeating.
                   Here you have Abdul, who bears a scar on his head from the same machete that killed his entire family as a child, not only using his engineering knowledge to save the lives of his people, but more importantly, to inspire the next generation of problem solvers to dream even bigger. It’s the type of thing that leaves you feeling a little bit of that contagious Rwandan optimism for the future and the incredible potential of us mere humans.
                            Human exceptionalism is real; it is part of our own experience and of human history. We thrive best when using our minds and morals unselfishly to solve problems for the improvement of our world.

AI = the death of art?

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File under "well said." XCIII

 



"We always plan too much and think too little.We resent a call to and hate unfamiliar argument that does not tally with what we already believe or would like to believe."

Joseph Schumpeter.









Just smarter apes?

 But, But, But … We’re 98% Similar to the Chimp!


Transposable elements just don’t make sense. These so-called “jumping genes” are segments of junk DNA that insert themselves at random in our genomes. That is the evolutionary interpretation of these genetic units, but how and why do they move about, and why don’t they wreak havoc on the genome? The answers to these questions, which have been emerging in recent years, is that transposable elements are exquisite, finely-tuned, highly-functional molecular machines that contradict evolutionary expectations. Evolutionists have a long, failed history of presumed disutility—after all, the world arose by chance, surely it doesn’t work very well—and transposable elements are just one more example of this failed prediction. But the junk-to-hero story is only one of three ways that transposable elements utterly demolish evolutionary theory. The other two prongs in this Darwin-destroying triad are serendipity and pattern.

By serendipity, I am referring to the rather awkward findings, which are undeniable at this point, that if evolution is true, then it must have come about by highly complex, non adaptive, mechanisms. From diploid genetics to horizontal gene transfer, alternate gene splicing, genetic regulation, epigenetics, mechanisms that cause adaptive mutations, and transposable elements, evolution must have bumbled along by luckily constructing fantastically complex mechanisms. Those mechanisms would provide no immediate adaptive value, yet somehow would persist and become vital agents in evolutionary history. Simply put, evolution must have created evolution in a most unlikely (astronomically unlikely) set of circumstances. That’s serendipity, not science, and transposable elements heaps more fuel onto the fire.

By pattern, I am referring to another set of awkward findings, again undeniable, that the pattern of structures observed across the species consistently contradicts evolution’s predictions. One of those contradictions are the enormous differences found in otherwise allied species.

All three of these contradictions—disutility, serendipity, and pattern—are on display this week in new, systematic study of transposable elements out of Didier Trono’s lab in Switzerland. The study details the interactions between transposable elements and a class of proteins. The findings indicate the complexity and interdependency of these molecular mechanisms. As the press release admits:
                          Long considered as junk DNA, transposable elements are now recognized as influencing the expression of genes. … the extent of this regulation and how it is harnessed were so far unknown. EPFL scientists have now taken the first extensive look at a family of ~350 human proteins, showing that they establish a complex interplay with transposable elements … KZFPs can convert transposable elements in exquisitely fine-tuned regulatory platforms that influence the expression of genes, which likely takes place at all stages of development and in all human tissues. … It is a highly combinatorial and versatile system … As a field, epigenetics has come into prominence in recent years, revealing a previously unimagined complexity and elegance in genetics.
                Not exactly junk DNA. And of course all of this would require large amounts of serendipity. For evolutionists are now forced to say that transposable elements would have to have played a, err, key role in evolution itself. Evolution would have had to have constructed this highly specific, detailed, system including hundreds of proteins and genetic elements, with hundreds of specific interactions, providing no immediate benefit. As Trono explains:
                    The vast majority of KZFPs binds to specific motifs in transposable elements. For each KZFP we were able to assign one subset of transposable elements, and also found that one transposable element can often interact with several KZFPs.
                                     Finally, all of this contradicts the expected common descent pattern. This failure has become so common we now have non evolutionary terminology, such as “species-specific” and “lineage-specific.” The paper uses the term “species-restricted”:
                       KZFPs partner with transposable elements to build a largely species-restricted layer of epigenetic regulation
                      Species-restricted? In other words, the designs we are discovering in biology are unique to particular species. This is precisely the opposite of what evolution expects. Note also the teleological language (which as usual is evident in the infinitive form): The proteins “partner” with the transposable elements “to build” a largely “species-restricted” layer of epigenetic regulation. This is a classic example of evolution’s absurd creation story language.

The contradictory pattern was, of course, unsuspected. As Trono explains:
                KZFPs contribute to make human biology unique. Together with their genomic targets, they likely influence every single event in human physiology and pathology, and do so by being largely species-specific -- the general system exists in many vertebrates, but most of its components are different in each case. … This paper lifts the lid off something that had been largely unsuspected: the tremendous species-specific dimension of human gene regulation.
                      Yes, it was largely unsuspected. For what these findings reveal is a tremendous species-specific dimension of human gene regulation. In other words, we would need proteins and genetic elements to evolve, via independent and yet interdependent, random mutations, to construct an entirely new set of genetic regulation instructions. This is astronomically unlikely, no matter how many millions of years are available. From a scientific perspective, these findings demolish evolution.

Tuesday, 28 March 2023

The salt of the earth

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On the father of the bomb.

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The pale horse on the rampage.

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AI's moral deficit?

 Robert J. Mark on AI’s Glaring Errors


Robert J. Marks contributed a piece at The Daily Caller this week on artificial intelligence, ChatGPT, and the manifold problems of new AI systems like Google’s Bard and older ones such as Amazon’s Alexa. Dr. Marks directs Discovery Institute’s Bradley Center and is author of the recent DI Press Book Non-Computable You. Despite the confidence in new AI coming from Big Tech executives, it makes quite glaring mistakes, although Marks believes AI has its genuine uses and benefits. Snapchat’s chatbot “My AI” gave advice about how to hide the smell of pot and alcohol to someone posing as a disgruntled teenager. Microsoft’s Bing bot professed its love for a tech journalist. A Google app made egregiously racist errors. ChatGPT is also politically biased despite claiming neutrality. 

Marks writes, 
                         Many warn of the future dangers of artificial intelligence. Many envision AI becoming conscious and, like SkyNet in theTerminator franchise, taking over the world (This, by the way, will never happen). But make no mistake. LLMs are incredible for what they do right. I have used ChatGPT many times. But user beware. Don’t trust what an LLM says, be aware of its biases and be ready for the occasional outlandish response.

ROBERT MARKS, MARKS: FROM POLITICAL BIAS TO OUTLANDISH DARES, HERE’S WHY ROBOTS CANNOT REPLACE US | THE DAILY CALLER 
                                             Marks encourages readers to try out ChatGPT and come to their own conclusions. Be sure to read the rest of his article Here



And yet even more primeval tech Vs Darwinism.

A Power Grid in Muscle Cells Has Profound Design Implications


A finding announced in Nature represents a blockbuster for intelligent design. We knew about ATP synthase — that rotary engine that uses proton flow to create “batteries” of energy-packed ATP molecules. Those motors in the mitochondria are arranged along folds (cristae) in the mitochondrial membranes to maximize their output.

But researchers have learned that the mitochondria themselves are connected by electrical wires in a vast intracellular network. This allows us to see another level in the hierarchy of design in the cell.

The findings are of revolutionary significance. Skeletal muscle cells were known to have many mitochondria, but it was not clear how the products of ATP production, called metabolites, became distributed throughout the cell. Many assumed it was by diffusion, or simple spreading out of molecules from regions of high concentration to areas of low concentration. The truth is far more exciting. Research News from the National Institutes of Health explains:
                 A new study overturns longstanding scientific ideas regarding how energy is distributed within muscles for powering movement. Scientists are reporting the first clear evidence that muscle cells distribute energy primarily by the rapid conduction of electrical charges through a vast, interconnected network of mitochondria — the cell’s “powerhouse” — in a way that resembles the wire grid that distributes power throughout a city. The study offers an unprecedented, detailed look at the distribution system that rapidly provides energy throughout the cell where it is needed for muscle contraction. 
                    
Introducing the “Mitochondrial Reticulum”

Diffusion is too slow for a fast-acting muscle cell. Electricity, though, is fast. The same proton-motive force that powers ATP synthase is conducted along cellular wires, the researchers found. You’ve heard of the endoplasmic reticulum. They’re calling this one the “mitochondrial reticulum” — a conductive pathway for energy distribution. The Editor’s Summary of the paper puts it this way:
           How is energy distributed within the cell? In the skeletal muscle, energy distribution has been proposed to occur through metabolite-facilitated diffusion, although genetic evidence has raised questions about the importance of this mode of distribution. Using various forms of high-resolution microscopy, Robert Balaban and colleagues explore whether the mitochondria themselves — as well as actually generating the energy — also have a role in its distribution. They find that they do, by forming a conductive pathway throughout the cell in the form of a proton-motive force. Throughout this network, the mitochondrial protein localization seems to be varied, allowing optimized generation and utilization of the mitochondrial membrane potential. This energy distribution network, which depends on conduction rather than diffusion, is potentially extremely rapid, thereby enabling muscle to respond almost instantaneously to new energy demands.
                   Not only is the system extremely fast, it is well organized. The Abstract states:
                      Within this reticulum, we find proteins associated with mitochondrial proton-motive force production preferentially in the cell periphery and proteins that use the proton-motive force for ATP production in the cell interior near contractile and transport ATPases. Furthermore, we show a rapid, coordinated depolarization of the membrane potential component of the proton-motive force throughout the cell in response to spatially controlled uncoupling of the cell interior. We propose that membrane potential conduction via the mitochondrial reticulum is the dominant pathway for skeletal muscle energy distribution.
                          The mitochondrial reticulum was known before, but scientists had not previously seen that it conducts electricity. The potential of this discovery to shed light on muscular dystrophy, heart disease, and other disorders is apparent.

The images in the paper even look like a power grid. More:
                          For the current experiments, the NIH scientists collaborated in a detailed study of the mitochondria structure, biochemical composition, and function in mouse skeletal muscle cells. The researchers used 3D electron microscopy as well as super-resolution optical imaging techniques to show that most of the mitochondria form highly connected networks in a way that resembles electrical transmission lines in a municipal power grid.
                     
A Case of Design Prediction

It’s clear why this is a superior design to diffusion. Strenuous exercise can raise the power demands of a muscle cell by 100-fold. “Researchers have suspected that a faster, more efficient energy pathway might exist but have found little proof of its
    existence — until now,” we read. That’s a case of design prediction!

Robert Balaban of the National Heart, Lung, and Blood Institute (NHLBI), a co-leader of the team, tells more about how well-optimized the organization of this power grid is. 
                The study provides unprecedented images of how these mitochondria are arranged in muscle. “Structurally, the mitochondria are arranged in such a way that permits the flow of potential energy in the form of the mitochondrial membrane voltage throughout the cell to power ATP production and subsequent muscle contraction, or movement,” Dr. Balaban explained. Mitochondria located on the edges of the muscle cell near blood vessels and oxygen supply are optimized for generating the mitochondrial membrane voltage, while the interconnected mitochondria deep in the muscle are optimized for using the voltage to produce ATP, Balaban added.
                   This implies another level in the design hierarchy: not only is the power grid well organized inside the cell, but the cells are organized in the muscle tissues for the optimum utilization of the power where it is needed most.
                  
Implications for Intelligent Design

The implications of this spectacular discovery for intelligent design are profound. To see why, we must remember that muscles first appear in the Cambrian explosion. Many of the Cambrian phyla that burst on the scene had muscles for contraction (jellyfish), crawling (worms), fin movement (Anomalocaris and Metaspriggina, the vertebrate fish), and coordinated action of jointed appendages (trilobites and other arthropods). Most of the Cambrian animals used muscles in various ways. Muscles are but one of many new cell types that appear suddenly, fully functional, across multiple phyla in the early Cambrian.

As Stephen Meyer emphasizes in Darwin’s Doubt, these new cell types are arranged in a hierarchy: tissues, organs, systems — and ultimately, integrated body plans. This hierarchical arrangement of complex parts for unified function challenges all undirected mechanisms such as natural selection. It takes foresight — a plan for a functional goal and the means to achieve it — to bring parts together into a hierarchical arrangement that works. The film Darwin’s Dilemma illustrates this point as well. In our uniform experience, Meyer argues, the only cause capable of doing that is intelligence. 

Now we can extend this hierarchical thinking into the arrangement inside one new cell type in a Cambrian animal: a muscle cell. That optimal hierarchical arrangement, furthermore, extends downward into the intracellular environment and upward into the tissue in which the cell resides. It’s hierarchy all the way down.
                 
                  

Secular humanism's Homer?

 Rescuing Evolutionary Theory from Darwinian Mythology


On a new episode of ID the Future, historian of science Michael Keas begins a two-part conversation with Robert Shedinger, the Wilford A. Johnson Chair of Biblical Studies and Professor of Religion at Luther College and author most recently of The Mystery of Evolutionary Mechanisms: Darwinian Biology’s Grand Narrative of Triumph and the Subversion of Religion. Shedinger reports on the contrast between Darwin’s private view of his theory of natural selection and the public view as detailed in his published work. Shedinger also notes the deficiency in evidence for Darwin’s proposal, despite claims to the contrary from his followers and evangelizers today. Download the podcast or listen to it Here

Monday, 27 March 2023

The science acknowledges the thumb print of JEHOVAH?

 Scientific Paper Argues Antarctic Icefish “Designed to Utilize Hemoglobinless Blood”


As Emily Reeves has Mentioned, a peer-reviewed paper in BIO-Complexity published tackles the question of the origin of how certain fish species live in extremely cold Antarctic waters. Titled “The Cardiovascular System of Antarctic Icefish Appears to Have Been Designed to Utilize Hemoglobinless Blood,” and authored by medical researcher Gregory Sloop, the paper argues that, “The circulatory system of Antarctic icefish may have been Designed to prevent high blood viscosity at low temperatures by taking advantage of the increased solubility of oxygen at low temperatures, allowing use of hemoglobin-free blood.” He argues that this complex system “could not have evolved via a series of gradual steps” because: 
                  The hemoglobinless phenotype requires simultaneous customization of the heart, vasculature, and blood, including its viscosity. Simultaneous, coordinated acquisition of multiple unique features, as required by the absence of hemoglobin, is inconsistent with Darwinian evolution, which postulates that species develop by small, incremental changes over time.

More Cold, More Viscous

When liquids become cold they tend to become more viscous. Sloop observes, however, that “the viscosity of icefish blood at its native temperature, approximately 0°C, is very similar to that of human blood at 37°C.” Fish that lives in very cold waters, such as Antarctic icefish, must therefore solve a problem: How are they able to pump blood through their bodies at such low temperatures? 

One way Antarctic icefish solve the problem is by having no erythrocytes (red blood cells) in their blood. So how do they deliver oxygen throughout their bodies? Some believe it’s due to nitrous oxide (NO) dissolved in the bloodstream, which actually causes hypoxia in icefish tissues. But Sloop maintains that it is thanks to “a customized cardiovascular system [rather] than a conventional one that was pressed into service when a mutation caused the loss of hemoglobin expression.” Some of these “cardiovascular customizations” include: 
                   Solubility of O2 increases with lower temperature, allowing the blood to carry more O2 at such a low temperature. 
Increased cardiac output. 
A special “high-output, low resistance circulation” where “trunk skeletal muscle capillaries are two to three times greater in diameter than those of typical teleosts, reducing vascular resistance” and “Icefish retinas are more densely vascularized than those of red-blooded notothenioids, increasing O2 delivery to this metabolically active tissue.”
This larger cardiac output and special vasculature require “a blood volume two to four times greater than that of red-blooded fish” which “in turn requires a customized heart that is heavier and has a larger stroke volume than that of red-blooded notothenioids.” As a result “stroke volume of the icefish heart is 6 to 15 times greater than in other teleosts.”
To sustain this larger heart, special heart contractile cells called “cardiomyocytes” are in the icefish “relatively large and contain a relatively large number of mitochondria.” Indeed, in one icefish species the percent of cardiomyocytes devoted to mitochondria are “the highest in any teleost and higher than in any vertebrate except for the Etruscan shrew.”
Special kidneys to accommodate the low-pressure blood circulation. 
Special “corpuscle” blood cells unique to icefish which convert carbon dioxide and water into carbonic acid. 
         
An “Example of Teleology in Biology”

The effect of all of these special features is to allow Antarctic icefish to have lower hematocrits (the percent volume used by red cells in the blood), which lowers blood viscosity, making it easier for the fish’s heart to pump blood under such cold conditions. Sloop concludes:
                    The customized icefish heart, vasculature, and blood form a system with mutually dependent parts. … The hemoglobinless phenotype requires simultaneous, coordinated acquisition of multiple unique features. This is difficult to explain with Darwinian evolution, which postulates that species develop by small, incremental changes over long periods. … Multiple customized components are necessary to utilize hemoglobinless blood. Actualizing the design for the icefish cardiovascular system requires each customized component to be in place simultaneously. This is more innovation than can be accomplished by random mutation as postulated in Darwinian evolution.
                      Sloop offers this potent observation: “Proponents of intelligent design see customizations to decrease blood viscosity as examples of teleology in biology.”

Sunday, 26 March 2023

On the danger of science as master rather than servant.

Aeschliman on Three Great Authors Critiquing Scientism


On a classic episode of ID the Future, Andrew McDiarmid concludes a two-part conversation with Michael D. Aeschliman, author of the revised and expanded The restoration of man: C. S. Lewis and the Continuing Case Against Scientism. Here Aeschliman places Lewis among a strong line of thinkers critiquing scientism. These include the philosopher and mathematician Blaise Pascal, who showed that scientific knowledge on its own could never be sufficient for being fully human, as well as the theologian and physicist Stanley L. Jaki, who brilliantly integrated science and theology. Aeschliman’s list also includes the great English author Jonathan Swift, whose satirical work skewered the illusions of scientific reductionism. Download the podcast or listen to it Here

Unsanctionable?


more on the struggle for the empire of God.

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On the crisis in the 51st American state?

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Chemistry Vs. OoL science.

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Journalism has fallen?

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Saturday, 25 March 2023

Commonsense on the rebound?

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Feminism's civil war?

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Friday, 24 March 2023

Waco revisited.

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Ask not what your country should do for you?

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the science concludes that that JEHOVAH may know a thing or two about engineering after all.

 Peer-Reviewed Paper Answers Claims of “Bad Design” of the Human Foot/Ankle


In a peer-reviewed paper published in BIO-Complexity, Bristol University engineering professor Stuart Burgess explains “Why the Ankle-Foot Complex Is a Masterpiece of Engineering and a Rebuttal of ‘Bad Design’ Arguments.” Brian Miller has
 previously Covered Professor Burgess’s arguments in a lecture, but those are framed as a response to arguments from ID-critics such as Jeremy DeSilva and Nathan Lents. Those critics claim that the human foot-ankle complex is sub-optimal because it reflects an unguided process where evolution attempted to convert a skeletal structure adapted for quadrupedal

 locomotion to bipedalism. Burgess argues in response that the ankle-foot complex “show a very high degree of complexity and fine-tuning” and “masterful engineering.” Moreover, “Engineering insight reveals a close relationship between form and function in the ankle, a relationship seen in its multiple bones and the layout of those bones” and the “five midfoot bones are needed to form the optimal kinematic and structural interface between the hindfoot and forefoot.”

Burgess observes that many who have studied the foot without a preconceived bias have recognized its “excellent design.” He quotes Leonardo da Vinci who called the human foot “a masterpiece of engineering and a work of art,” and more modern researchers who observe the “nearly effortless human gait” or who note that various foot structures “work in perfect synchronisation” because it is “superbly constructed for ambulation.” 

A Contrast with “Bad Design

In contrast, “bad design” proponents believe that most of the seven anklebones are pointless, poorly coordinated, and fundamentally a bad design because a “fused structure” would work better than “a joint with so many separate parts.” Burgess answers arguments that the ankle-foot performs poorly for bipedalism because it was originally evolved for quadrupedal locomotion by observing that such arguments “are based on circular reasoning and assumptions about what evolution could or could not do in the past.” He believes that “A better scientific approach to assessing the quality of design is to study the actual biomechanics and functions of the foot.”

Burgess observes that “The requirements for agile bipedal movement are extremely demanding.” After all, the foot must be “a compact multifunctioning precision device” which has to fulfill multiple requirements which are sometimes contradictory:
                     Act as a strong and stiff lever to propel the body forwards in walking and running. Joint movement is plantarflexion.

2. Act as a flexible platform to absorb shocks and adapt to uneven ground. Joint movements include dorsi-flexion, pronation, and supination.

3. Provide 3-point contact with the ground to allow standing on one or two legs and to enable controlled push-off from the ball of the feet. The control must involve fine adjustment of direction as well as power.
                          
Difficult and Contradictory Demands

Yet Burgess further notes that “The requirements of a stiff lever and flexible platform are difficult to achieve because they are contradictory. To achieve these two requirements the foot must have stiffness and flexibility in just the right places. In addition, the foot must have the ability to adjust stiffness through precise control of muscles.” The foot is able to accomplish this because it “has three interconnecting flexible arches that perform multiple functions in particular three-point contact with the ground, stiff lever for take-off and flexibility for shock absorption.” Burgess notes how well-designed these arches are:
                       There are several features that maintain the integrity of the arches: (i) foot arches segmented like a Roman arch, which induces compressive forces, particularly the bone that forms the keystone to the arch; (ii) short ligaments that tie adjacent bones together; (iii) longer ligaments (like the spring ligament) that tie the arch across multiple bones; (iv) muscle-tendon groups that act like a sling, pulling the arches upwards; and (v) muscles that stiffen the arch.
                      He further notes that the bones of the midfoot allow it to perform five main sub-functions, including providing a “flexible transverse arch,” “Load bearing structure during pronation,” “Kinematic interfaces for pronation-supination,” “Structural interface for longitudinal loads,” and “Stiffening of the medial arch.” 

Burgess also finds that “Another specialised design feature in the ankle-foot complex is the elastic hinge joints,” as some 17 of such joints allow “significant flexibility” in the foot and also aid in shock absorption. In fact, Burgess reports that these elastic hinge joints have at least five sub-functions, including “(i) flexibility; (ii) load-bearing; (iii) energy storage; (iv) failsafe design; and (v) ultra-low friction.” 

Bad-design proponents have asked why there are paired bones at the bottom of the leg above the ankle instead of a single bone. Burgess notes there are good reasons for this as fibula is “well known to provide stability to the ankle joint” via “a type of linkage system with multiple bars.” He cites two specific advantages to having a fibula bone:
                 One advantage of the fibula is that it increases the moment arm (mechanical advantage) of muscles acting on the ankle-foot complex. A second advantage is that the fibula increases the attachment area for muscles and therefore allows more muscle to act on the joint.
                  
Answering Bad Design

After providing this review of the engineering functions of the ankle-foot complex, Burgess is able to address claims that many foot and angle bones are functionless. In reality, “this paper has shown that all the bones of the ankle-foot complex have very important roles in the specialized design features. In particular, the five bones of the midfoot have multiple functions.” He also definitively shows that the fibula bone is necessary because it “provides essential stability to the ankle joint during pronation by forming a multi-bar linkage mechanism.” Burgess shows that a fused ankle structure would not function better because “It is well known in the medical field that ankle fusions lead to a degradation of ankle performance” and relative movement of ankle bones affords various functions, including shock absorption. 

A major anti-design argument is that ankles are prone to sprains or other injuries, but Burgess notes that this confuses misuse with bad design:
                  The importance of this differentiation can be illustrated by analogy with a modern car. Most modern cars are well designed and very reliable when in good condition and used properly. However, despite the high quality of design, a modern car will fail if overloaded or neglected, or if it is simply very old. Therefore, when considering malfunctions in joints it is important to check why there was a malfunction. If the ankle-foot complex malfunctions due to overload, neglect, or health issues, this does not mean the design can be judged as bad.
                Burgess ends with four conclusions:
                        There are four highly specialised design features in the ankle-foot complex

2. The ankle-foot complex is superior to human-engineered joints

3. Lents’s bad design arguments are contrary to scientific evidence

4. Engineering insight explains form and function
               This last point is crucial because it shows that the very design and structure of the ankle-foot complex must exist to for it to perform its functions. According to Burgess, the system exhibits “very sophisticated engineering design.”

Pre-human powered flight v. Darwin.

 Fossil Friday: The Abrupt Origin of Winged Insects


This Fossil Friday features Lithomantis varius, a large fossil insect from the Carboniferous (Namurian) brickwork quarry of Hagen-Vorhalle in Germany, which is one of the most ancient fossil localities for winged insects and dates to about 318 million years ago. Lithomantis belongs to the winged insect order Paleodictyoptera, which only existed in the Palaeozoic era.

Insect wings are extremely complex structures that are highly adapted to their function Delitzschalan as flight organs. They have a fan-like plicated structure to give the wing surface stability; additionally they are enforced by a complex wing venation; the wing is also supplied with sensory hairs; and the wing base has a highly complex arrangement of articulatory plates to allow for sophisticated movement, enabled by an associated muscular and neural system.

According to Darwinism, the evolution of such a system would certainly have required a plethora of intermediate stages that brought this wonderful locomotory apparatus into being by an accumulation of many small changes over a long period of time. Since paleontologists have discovered thousands of fossil insects from the Paleozoic, we have certainly also found at least some of these transitional forms in the evolution of insect wings!? At least one? Nope, not a single one.

The oldest fossil winged insects belong the orders Palaeodictoptera (e.g., Delitzschala) and to the giant dragonfly order Meganisoptera, thus they were already equipped with the complete wing apparatus. There is not a single transitional form, so that the leading textbook on insect evolution, by Grimaldi & Engel (2005: 160), admitted: “An insect equivalent of an Archaeopteryx remains elusive but certainly existed.” Apparently, the engineering marvel of insect wings came into being abruptly rather than gradually, which is inexplicable with unguided evolution but quite expected with intelligent design.

Common sense has fallen?

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Common sense re:Common ancestry?

 Peer-Reviewed Paper Shows Vertebrate Embryonic Variation Contradicts Common Ancestry


Evolutionary biologists often argue that vertebrate embryos develop in highly similar manners, reflecting their common ancestry. But a peer-reviewed paper in BIO-Complexity, by David Swift (author of Evolution Under the Microscope), provides an insightful review on the subject. The Article is titled, “The Diverse Early Embryonic Development of Vertebrates and Implications Regarding Their Ancestry.” Swift shows that, despite common claims, vertebrates do not develop similarly, according to the predictions of evolution. 

He opens by framing his thesis:
                 It is well known that the embryonic development of vertebrates from different classes (e.g., fish, reptiles, mammals) pass through a “phylotypic stage” when they look similar, and this apparent homology is widely seen as evidence of their common ancestry. However, despite their morphological similarities, and contrary to evolutionary expectations, the phylotypic stages of different vertebrate classes arise in radically diverse ways. This diversity clearly counters the superficial appearance of homology of the phylotypic stage, and the plain inference is that vertebrates have not evolved from a common vertebrate ancestor. The diversity extends through all stages of early development — including cleavage and formation of the blastula, gastrulation, neurulation, and formation of the gut and extraembryonic membranes.
                         Now intelligent design does not require common ancestry to be false, but even a guided form of common ancestry might lead to different predictions from strictly unguided descent with modification. Thus, Darwin and subsequent evolutionists such as Ernst Haeckel found embryology to be a crucial line of evidence supporting Darwin’s thesis. According to Swift, common ancestry predicts that vertebrate development should exhibit striking homologies. But more than that, “If common ancestry is the explanation for homologies, not only should homologous organs be derived from equivalent embryonic tissues (the cardinal criterion for homology) but they should also develop by comparable processes.”
                       

Very Different Pathways

The crux of Swift’s thesis is that although vertebrate embryos do pass through a similar “phylotypic stage,” the pathways of development are very different: 
                   [D]espite their morphological similarities and contrary to evolutionary expectations, the striking fact is that the “phylotypic stages” of different groups of vertebrates arise in remarkably diverse ways, even with key tissues such as the germ layers (see below) deriving from completely different early embryonic sources. These observations clearly refute the presumed evolutionary homology of the vertebrate phylotypic stage, and hence undermine the inference of common ancestry based on that supposed homology.
                   He reprints the “hourglass model” of vertebrate development and points out that this is merely an “observation” about development — not an explanation of how it arose:


From: Irie N, Satoh N, Kuratani S (2018) The phylum Vertebrata: A case for zoological recognition. Zoological Lett. 4(32):1–20. doi:10.1186/s40851-018-0114-y, under Creative Commons License

One of the key stages of development that leads to this similar “phylotypic stage” is gastrulation, which Swift notes is crucial because it establishes the basic body plan and “leads to the establishment of the germ layers — ectoderm, mesoderm and endoderm — from which all of the body’s tissues are derived.”
                  
Differences in Vertebrate Development

Swift cites various specific differences in vertebrate development to make his case, especially in gastrulation. He predicts that “from an evolutionary perspective we would surely expect gastrulation to be ‘conserved’” but finds that “for almost all of the major classes of vertebrates” there are key differences in gastrulation, including “the mechanism of gastrulation is significantly different from any of the others,” and “the source tissues of the germ layers are different.” 

After reviewing mechanisms of gastrulation in various vertebrate classes, Swift notes that “the wide variety of structures of the blastulas of different classes of vertebrate challenges the view that the resultant embryonic tissues can be considered equivalent or homologous.” Specifically, in different types of vertebrates different parts of the blastula ultimately become the embryo itself. He describes these differences as follows:

Chondrichthyans (lancelets): “It is a one-cell thick epithelial layer, forming the upper surface of the blastula.”
Teleosts (bony fish, e.g., zebrafish): “It is a multiple-cell layer, beneath the overlying enveloping layer.”
Amphibians: “It is the whole of the blastula, comprising the multilayered dome of the upper hemisphere and the mass of cells in the lower hemisphere.”
Reptiles and birds: “It is the upper surface of the blastula, comprising a single-cell thick epithelial layer, overlying the hypoblast.”
Placental mammals (e.g., primates): “It is part of the inner cell mass, within the outer trophoblast.”
He cites further differences between which cells become the endoderm and which become the mesoderm, noting:
                     in amniotes (reptiles, birds, mammals) cells that are internalized arise from a central area of the epiblast, i.e., the presumptive endoderm and mesoderm are surrounded by presumptive ectoderm; whereas
in anamniotes (chondrichthyans, teleosts, amphibians) the cells that internalize are from the edge of the epiblast, i.e., the presumptive endoderm and mesoderm surround the presumptive ectoderm.
                Swift summarizes major differences in the mechanisms of gastrulation as follows:
                        Chondrichthyans: by cells rolling over a posterior overhang of the epiblast.
Teleosts: by involution around the edges of the epiblast as it spreads around the yolk.
Amphibians: by involution through an annular blastopore.
Reptiles: by involution through a canal-like blastopore.
Birds: by cells ingressing through a primitive streak, formation of the primitive streak being accompanied by growth of an underlying endoblast.
Placental mammals: by cells ingressing through a primitive streak.

Three Substantial Distinctions”

Swift thus finds that these diverse modes of development cannot be considered homologous:
                     In the light of these three substantial distinctions — the different overall structure of the blastulas, the different parts of the blastula that become the embryo, and the different relative positions of the presumptive ectoderm and mesoderm/endoderm in amniotes and anamniotes — there is no doubt that the tissues that become the embryo are not equivalent, and hence are far from being homologous across the various vertebrate classes.
                According to Swift, these fundamental differences in early vertebrate mechanisms of development during gastrulation suggest that vertebrates do not share a common ancestry:
            The straightforward conclusion to draw from this radical diversity of their early embryonic development is that it shows the vertebrates have not evolved from a common vertebrate ancestor. This conclusion can be avoided only if there are credible explanations for how such diversity of early development might have arisen from the development prevailing in a common ancestor (whether or not similar to present-day cephalochordates) in an evolutionary way, via changes that (i) had a realistic probability of occurring, (ii) maintained viability, and (iii) offered, in most cases, significant advantage that could be favored by natural selection.
                   Meeting these evolutionary requirements poses a great challenge, however. Swift quotes a prominent developmental biologist, Rudolf Raff, who wrote: “One might reasonably expect mechanisms of early development to be especially resistant to modification because all subsequent development derives from early processes.” Swift calls this a “commonsense conclusion” because the complexity of vertebrate development demands that many coordinated modifications would be required to fundamentally change how development proceeds. He thus finds that “because of the interdependence of the mechanisms that are involved, constructive changes to embryonic development must entail coordinated production of and/or changes to several genes, e.g., for transcription factors and the DNA sequences on which they act, which is prohibitively improbable.” 

This leads to a “waiting time” problem where multiple coordinated change would be required to transition from one developmental regime to another, posing “a formidable challenge to supposed evolutionary scenarios” as generating these changes would be “generally far in excess of the time available.”