And still even yet more on the real world's anti-Darwinian bias.

The Blink of an Eye — And More Wonders of Human Body Design
Evolution News | @DiscoveryCSC

Darwinists insist on your body’s “poor design.” By contrast, a prediction of intelligent design for biology is that phenomena should appear more functionally complex and elegantly coordinated the closer one looks. Evolutionist cavils aside, this is certainly true for the human body.

Vision

We blink all day long, once about every 5 seconds. Why doesn’t the world go dark in those moments? How do we perceive a continuous image? “The brain seems to remember the percepts that have just happened,” an article in Science Dailysays. “Scientists have now identified a brain area that plays a crucial role in perceptual memory.” At the German Primate Center, they found the spot where visual information is stored briefly during each eye blink. “Our research shows that the medial prefrontal cortex calibrates current visual information with previously obtained information and thus enables us to perceive the world with more stability, even when we briefly close our eyes to blink,” says the lead author of a paper in Current Biology. This implies a process of calibration, interpolation, and calculation happening literally in the blink of an eye.

“Ghost images” can be detected by the human vision system, an article inLive Science says. These are not direct images that we are familiar with, but rather computed images arrived at by multiplying the light in each pixel from a projected scene onto a background scene. The product produces the ghost image, but it can only be perceived under the right circumstances.

Experiments with participants viewing a superimposed checkerboard on a background photo showed that the ability to see the ghost image is a function of the eye’s refresh rate. The photo only became visible when a single-pixel detector collected the light from each pixel and then fed it into a projector at the right speed. Reporter Stephanie Pappas says this is akin to the optical illusion of seeing a movie when the frame rate matches the eye’s refresh rate. 

The reason this works, [Daniele] Faccio said, is that the human eye has a slow refresh rate. It’s not unlike the reason that movies work: When images are flickered on the screen faster than this refresh rate, it creates the illusion of smooth movement.

The eye “is very fast in acquiring the information,” Faccio said. “It’s just very slow in getting rid of it.”

The researchers figured out that the flickering patterns remained in the eye’s “memory” for about 20 milliseconds, slowly fading out over that time. If the 20-millisecond patterns overlap, the eye sums them up like a movie, allowing the ghost image to emerge.

Although ghost images are unlikely to appear in natural settings, the experiments provide a new way for neuroscientists to understand vision. For design advocates, they open windows into the moment-by-moment calculations that our eyes and brain have to perform to give us a smooth picture.

Olfaction

What we perceive as odors are collections of molecules. Why similar molecules produce very different perceptions of smell has long been a puzzle to physiologists, making odor classification difficult. Is there a way to classify odors, the way audible tones can be classified by frequency?The Salk Institute looked into this “unsolved problem,” hoping to find a pattern that might allow scientists to predict how a molecule (or combination of molecules) would smell. They found that mapping molecules in 2D was too simplistic. Patterns emerged only when they mapped the molecules onto a hyperboloid, a shape similar to a Pringles potato chip.

When the team looked at how the molecules clustered on this surface, they found there were pleasant and unpleasant directions, as well as directions that correlated with acidity or how easily odors evaporate from surfaces. These observations now make it easier to construct pleasant odor mixtures to use, for example, in artificial environments (such as a space station).

The paper in Science Advances explains why this pattern makes sense in nature:

In the natural environment, the sense of smell, or olfaction, serves to detect toxins and judge nutritional content by taking advantage of the associations between compounds as they are created in biochemical reactions. This suggests that the nervous system can classify odors based on statistics of their co-occurrence within natural mixtures rather than from the chemical structures of the ligands themselves.

Meanwhile, at the Monell Center in Philadelphia, scientists learned something new about “mysterious sensory cella” in the nose adjacent to the olfactory sensory neurons, called microvillous cells. “The findings suggest that the so-called microvillous cells (MVCs) may protect the vulnerable olfactory epithelium by detecting and initiating defenses against viruses, bacteria, and other potentially harmful invaders.” MVCs may also helped regenerate damaged cells in the olfactory epithelium. This suggests “multiple levels of protection in the airways,” says a co-author of the paper in  PLOS ONE that, fortunately, appears more interested in the function of these cells than their evolution. 

Mother’s Milk

Two news items show the benefits of human milk for newborns. Scientists at the University of Edinburgh find that “Breast milk may help babies’ brain development.” Pre-term babies showed better brain development when fed breast milk instead of formula. Brain scans were performed on 47 pre-term babies at 40 weeks that had been delivered at 33 weeks

The team also collected information about how the infants had been fed while in intensive care — either formula milk or breast milk from either the mother or a donor.

Babies who exclusively received breast milk for at least three-quarters of the days they spent in hospital showed improved brain connectivity compared with others.

The effects were greatest in babies who were fed breast milk for a greater proportion of their time spent in intensive care.

HealthDay  reports on a paper in the journal Pediatrics where scientists compared the “healthy weight trajectory” of babies who were fed directly from the breast, or by pumping, or by formula. Healthy weight gain was best for those babies with direct breast feeding, scientists found. “Researchers stressed that breast milk, in any form, is better than formula,” they said. “But they said the findings support the notion that the method of feeding matters, too.” Often this is difficult for mothers having to work. A healthy society should promote this natural function of mother and baby.

Liver

The liver is appropriately named; it wants to live. It has an uncanny ability to regenerate itself, and can regrow 70 percent of its mass in a few weeks if damaged, and function like new. Researchers at the University of Illinois wondered how it does that at the molecular level. The secret involves signaling and alternative splicing that puts the liver back into a neonatal state:

“We found that the liver cells after birth use a specific RNA-binding protein called ESRP2 to generate the right assortment of alternatively spliced RNAs that can produce the protein products necessary for meeting the functional demands of the adult liver,” said graduate student Sushant Bangru, the lead author of the study. “When damaged, the liver cells lower the quantity of ESRP2 protein. This reactivates fetal RNA splicing in what is called the ‘Hippo signaling pathway,’ giving it instructions about how to restore and repopulate the liver with new and healthy cells.”

Conclusions

Many non-living objects, such as crystals and metals, look the same practically all the way down. Living things, by contrast, become more wondrous as you zoom in from organism to organ to tissue to cell to nucleus. New imaging techniques are bringing wonders into focus that were unimaginable for most of human history. If ever there was a heyday for intelligent design.

Mssrs. Denton and Berlinski v. Darwinism.

Denton, Berlinski: Primary Objections to Neo-Darwinism
Evolution News | @DiscoveryCSC

If you had an opportunity to confute and confound your Darwinist friends, but a limited amount of time in which to do it, what challenge would you put to them? Discovery Institute Senior Fellows David Berlinski and Michael Denton are both long-time critics of neo-Darwinism. On a classic episode of ID the Future, responding to this query from Evolution News editor David Klinghoffer, they discuss their primary objections to neo-Darwinian theory.

Download the podcast or listen to it here.

For Berlinski, a mathematician and author of The Deniable Darwin, the problem is quantitative and methodological. For Denton, a geneticist and author of the new Discovery Institute Press book Children of Light: The Astonishing Properties of Light that Make Us Possible, the problem is empirical. Don’t miss this engaging discussion.

Darwinian spin doctors' rose colored spectacles are of no help with the Cambrian explosion.

"Molecular Clock" Can't Save Darwin from the Cambrian Explosion
Evolution News & Views October 28, 2015 3:59 AM


Current Biology has published yet another attempt to explain away the Cambrian explosion. On reading certain parts, you might think the authors, including Maximilian Telford, Philip Donoghue, and Ziheng Yang, have solved the problem. Indeed, their first Highlight in the paper summary claims, "Molecular clock analysis indicates an ancient origin of animals in the Cryogenian." (Cryogenian refers to the Precambrian "cold birth" era about 720 to 635 million years ago.) By itself that statement would be very misleading, because the title of the open-access paper is pessimistic: "Uncertainty in the Timing of Origin of Animals and the Limits of Precision in Molecular Timescales."

Yang appeared briefly in Stephen Meyer's book Darwin's Doubt with bad news. Meyer cited a paper Yang co-authored with Aris-Brosou in 2011 showing that molecular clock analyses are unreliable. They "found that depending on which genes and which estimation methods were employed, the last common ancestor of protostomes or deuterostomes (two broadly different types of Cambrian animals) might have lived anywhere between 452 million years and 2 billion years ago" (Meyer, p. 106).

Nothing has changed since then. The bottom line after a lot of wrangling with numbers, strategies, and analyses is that all current methods of dating the ancestors of the Cambrian animals from molecular clocks are imprecise and uncertain. They cannot be trusted to diffuse the explosion by rooting the animal ancestors earlier in the Precambrian.

Although a Cryogenian origin of crown Metazoa agrees with current geological interpretations, the divergence dates of the bilaterians remain controversial. Thus, attempts to build evolutionary narratives of early animal evolution based on molecular clock timescales appear to be premature. [Emphasis added.]
Check out the euphemisms. Translated into plain English, it means, "We can't tell our favorite evolutionary story because the clock is broken, but we're working on it."

In this new paper, they provide the latest and greatest analysis of molecular clock data so far. It's clear they believe that all the data place the root of the divergence in the Ediacaran or earlier, 100 million years or more before the Cambrian, but can they really defend their belief? They have to admit severe empirical limits:

Here we use an unprecedented amount of molecular data, combined with four fossil calibration strategies (reflecting disparate and controversial interpretations of the metazoan fossil record) to obtain Bayesian estimates of metazoan divergence times. Our results indicate that the uncertain nature of ancient fossils and violations of the molecular clock impose a limit on the precision that can be achieved in estimates of ancient molecular timescales.
Perhaps, a defender might interrupt, the precision, admittedly limited, is good enough. But then, there are those pesky fossils! The molecular clocks are fuzzily in agreement about ancestors in the Precambrian, but none of them have support from the very best observational evidence: the record of the rocks. Even the phyla claimed to exist before the explosion are contested:

Unequivocal fossil evidence of animals is limited to the Phanerozoic [i.e., the modern eon from Cambrian to recent, where animals are plentiful]. Older records of animals are controversial: organic biomarkers indicative of demosponges are apparently derived ultimately from now symbiotic bacteria; putative animal embryo fossils are alternately interpreted as protists; and contested reports of sponges, molluscs, and innumerable cnidarians, as well as putative traces of eumetazoan or bilaterian grade animals, all from the Ediacaran. Certainly, there are no unequivocal records of crown-group bilaterians prior to the Cambrian, and robust evidence for bilaterian phyla does not occur until some 20 million years into the Cambrian.
This severely limits their ability to "calibrate" the molecular clock. Meyer granted the possible existence of three Precambrian phyla (sponges, molluscs, and cnidarians). But there are twenty other phyla that make their first appearance in the Cambrian, many of them far more complex than sponges. What good are the molecular methods if you can't see any of the ancestors in the rocks?

The authors admit that the Precambrian strata were capable of preserving the ancestors if they existed.

No matter how imprecise, our timescale for metazoan diversification still indicates a mismatch between the fossil evidence used to calibrate the molecular clock analyses and the resulting divergence time estimates. This is not altogether surprising since, by definition, minimum constraints of clade ages anticipate their antiquity. Nevertheless, it is the extent of this prehistory that is surprising, particularly since the conditions required for exceptional fossil preservation, so key to evidencing the existence of animal phyla in the early Cambrian, obtained also in the Ediacaran.
The only way they can maintain their belief that the ancestors are way back earlier is to discount the fossil evidence as "negative evidence" and to put their trust in the molecular evidence. But how can they trust it, when the answers vary all over the place, depending on the methods used? One clever method is called "rate variation." Would you trust a clock that has a variable rate? How about one fast-ticking clock for one animal, and a slow-ticking clock for another?

When rate variation across a phylogeny is extreme (that is, when the molecular clock is seriously violated), the rates calculated on one part of the phylogeny will serve as a poor proxy for estimating divergence times in other parts of the tree. In such instances, divergence time estimation is challenging and the analysis becomes sensitive to the rate model used.
They try their trees with steady rates and with varying rates ("relaxed clock models" -- amusing term). They try data partitioning. They try Bayesian analysis. None of them agree. Meyer discussed molecular clock problems in detail in Chapter 5 of Darwin's Doubt. There's nothing new here. "Here we show that the precision of molecular clock estimates of times has been grossly over-estimated," they conclude. "....An evolutionary timescale for metazoan diversification that accommodates these uncertainties has precision that is insufficient to discriminate among causal hypotheses." In the end, these evolutionists have to admit that fossils would be much, much better:

Above all, establishing unequivocal evidence for the presence of metazoan clades in the late Neoproterozoic, as well as for the absence in more ancient strata, will probably have more impact than any methodological advance in improving the accuracy and precision of divergence time estimates for deep metazoan phylogeny. Realizing the aim of a timescale of early animal evolution that is not merely accurate, but sufficiently precise to effect tests of hypotheses on the causes and consequences of early animal evolution, will require improved models of trait evolution and improved algorithms to allow analysis of genome-scale sequence data in tandem with morphological characters.
Wait a minute; isn't that what Darwin provided? -- a model of trait evolution? Wasn't it natural selection of gradual variations? Let's parse this interesting quote that mentions Darwin:

The timing of the emergence of animals has troubled evolutionary biologists at least since Darwin, who was sufficiently incredulous that he considered the abrupt appearance of animal fossils in the Cambrian as a challenge to his theory of evolution by natural selection. There has been, as a result, a long history of attempts to rationalize a rapid radiation of animals through theories of non-uniform evolutionary processes, such as homeotic mutations, removal of environmental restrictions on larger body sizes, through to the assembly of gene regulation kernels --- proposed both as an explanation for rapid rates of innovation followed by subsequent constraint against fundamental innovation of new body plans after the Cambrian. Indeed, there have been explicit attempts to accommodate rapid rates of phenotypic evolution in the early Cambrian, compatible with these hypotheses and a semi-literal (albeit phylogenetically constrained) reading of the fossil record.
And yet our results, as have others before them, suggest that there is no justification for invoking non-uniform mechanisms to explain the emergence of animals and their phylum-level body plans.

That phrase "semi-literal (albeit phylogenetically constrained) reading of the fossil record" is curious. How else are you supposed to read it? They are saying that you have to read the fossil record with Darwin-colored glasses to see it correctly.
But they're trying to have it both ways. They want a slow-and-gradual fuse leading up to the Cambrian explosion (disliking "non-uniform evolutionary processes"), which requires a non-literal reading of the fossil record with Darwin glasses on, but they can't take the molecular data literally either, because it is so method-dependent. You can almost hear them crying out for fossils. As Meyer's book shows, the fossil record is more explosive now than it was in Darwin's time.

The Information Enigma Again

Notice how they mention "the emergence of animals and their phylum-level body plans." How do you get the information to build a phylum-level body plan? Once again, these authors ignore the information issue completely. They say, "Much of the molecular genetic toolkit required for animal development originated deep in eukaryote evolutionary history," skirting past that with a lateral reference to a paper about a microbe that had no animal body plan. Talk of "emergence" just doesn't cut it. What is the source of the information to build an animal body plan composed of multiple new cell types and tissues, with 3-D organization and integrated systems like sensory organisms, locomotion and digestive tracts? Is there an evolutionist who will please answer Meyer's primary challenge?

As we've seen over and over again, many Darwinian evolutionists think they have done their job if they can just push the ancestry back in time. The fossil record doesn't allow it, but even if it did, it wouldn't solve the information problem. Calling it "emergence" is unsatisfactory. Calling it "innovation" is unsatisfactory. Calling it latent potential waiting for environmental factors like heat or oxygen is unsatisfactory. Answer the question: what is the source of the information to build twenty new animal body plans that appeared suddenly in the Cambrian without ancestors? We have an answer: intelligence. What's yours?