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Sunday, 4 June 2023
Hopeful monsters of the deep vs. Darwinism.
Okeanos Explorer Searches The Deep Sea
What they have found is an array of incredible, and lowly (pun intended), creatures. Surely Ralph Cudworth and John Ray would have, by this point, doubled down on their infra-dignitatem argument that such creatures are beneath the Creator’s dignity. There must have been an intermediate creative force to account for the muck and its inhabitants, not to mention those bungles and errors we find in creation.
Isn't it amazing what those random mutations will come up with? (And no, natural selection doesn’t help).
Saturday, 3 June 2023
On confirmation bias re: genetic evidence for Darwinism
BioLogos and Vitellogenin Genes
Recently I have been responding to several articles by evolutionist Dennis Venema. Venema has made various arguments about how genetic evidences strongly support evolution and I have provided rebuttals to those claims. For instance, I explained Here that while Venema discusses evidences that are consistent with evolutionary expectations, he does not list or mention the substantial body of scientific findings that are inconsistent with evolution. This is a problem with the evolution literature: the scientific evidence is too often selectively presented. In fact, I have often seen evolutionists claim that there are no contrary evidences, and that the science fully backs evolution. This sort of confirmation bias presents a roadblock to meaningful discourse on the topic of origins.
Next Venema focused his claim on the specific case of human evolution, and the similarity between the human and chimpanzee genomes. Again, Venema made high claims about the evidence. He concluded: “These observations strongly support the hypothesis that our species arose through an evolutionary process.”
But, in fact, as I explainqed Here, there are several significant problems with this claim. For example, the chimpanzee and human genomes have differing patterns that do not fit evolutionary expectations. There is also a big difference between viruses in the genomes of humans and the other primates. Again, these differences do not fit the expected evolutionary pattern. Furthermore, the chimp-human genome beneficial differences are few and appeals to alternate splicing differences (another big difference between the genomes of humans and the other primates) to evolve humans lead to astronomically improbable pathways.
As always, I explained that the point is not that evolutionary explanations are not possible. Speculative explanations are always possible. Perhaps evolution did this, perhaps it did that. But that does not change the fact that the primate genomes do not “strongly support the hypothesis that our species arose through an evolutionary process,” as Venema and the evolutionists claim.
Next Venema focused even more narrowly on a particular genetic detail: human chromosome two, which he presented as a powerful example of an evolutionary confirmation. And yet as I explained here, not only did Venema not mention several scientific problems with his claim but the claim, even if true, would not demonstrate evolution as evolutionists claim. There is no evolutionary relationship revealed. Even if evolution were true, these data would give us no evidence for it. What was disturbing about this example was Venema’s recounting of a deceptive lecturing strategy he uses in presenting this topic in his class.
Next Venema presented pseudogenes which Venema argued are powerful and compelling evidences for common descent. It is, explained Venema, “one of the strongest pieces of evidence in favor of common ancestry between humans and chimpanzees (and other organisms).” And again, I explained, here and here, that there are several, fundamental, problems with this evolutionary claim.
In this case, however, Venema discussed his underlying religious belief that this evidence is a problem for creationism type theories. Venema was highlighting one of the important beliefs at the foundation of evolutionary thought. This belief, if true, does indeed require evolution to be true. But of course it is not falsifiable.
Vitellogenin genes
Now we move on to Venema’s next Topic , the vitellogenins. Vitellogenin genes are found in a wide range of species and, like most genes, perform multiple functions including helping to provide the nutrients in egg yolks. Also like most genes, the pattern they form amongst the species does not always correspond very well to the expected evolutionary pattern. Of course there are always explanations, and evolutionists draw upon a variety of mechanisms, including lineage-specific events, to explain the vitellogenin genes.
For example, this paper focuses on mosquito vitellogenin genes. It concludes that the genes arose by a series of duplication events, and that the pattern of duplication was different in each mosquito genus. The Paper also uses purifying selection, gene conversion, unequal crossover, and concerted evolution to explain the observed pattern of the mosquito vitellogenin genes, and concludes that these mechanisms must have also worked, independently, in other invertebrate species, and vertebrate organisms as well.
Similarly, this Paper examines the evolution of vertebrate vitellogenins and also draws upon a variety of events and lineage-specific mechanisms. As I have discussed many times, while the basic idea of evolution is that the species share common designs as a consequence of common ancestry, in fact biology is loaded with unique, one-off designs for which evolutionists need to appeal to “lineage-specific” evolution. Consequently evolution can explain a wide variety of observations and patterns, and this applies equally well to the vitellogenins.
Clearly evolutionary theory is fine with a range of patterns when it comes to the vitellogenins. Of course this is true for molecular, and morphological, designs in general, as we have seen many times. Designs can fall into an evolutionary common descent pattern, or not.
The advantage of this flexibility is that evolutionary theory can explain a wide range of observables. The disadvantages, however, are many. The theory becomes less parsimonious. It becomes more resistant to falsification. And it loses its evidential arguments. If a theory can explain A, and B, and C, … and so forth, then the finding of A is hardly compelling evidence for the theory.
Yet this is what Venema argues. The vitellogenin genes in chickens share a weak similarity with corresponding genetic segments in humans. Evolutionists view the human segments as pseudogenes—broken versions of vitellogenin genes inherited from their egg-laying ancestors. Given this vitellogenin similarity between humans and chickens, for example, evolutionists such as Venema incredibly conclude that, therefore, humans and chickens evolved by random mutations from a common ancestor. Not only does that not follow, but it takes Venema to the unlikely solution of random mutations creating humans and chickens, and of course all the other species.
Venema also argues that the similarity of the vitellogenin genes between humans and chickens extends to, and is all the more confirmed by, their positioning within their respective genomes. But this argument from synteny is no different from what we saw above. When there is a loss of synteny evolution is not harmed, and the theory has another set of explanatory mechanisms available for just about any outcome. If the vitellogenin genes had been in a different order, evolution could have explained it just fine.
Affirming the consequent
In spite of these problems with his argument, Venema is enthusiastic about this evidence. In fact his enthusiasm leads to the fallacy of affirming the consequent, as he equates shared synteny (genes with similar positioning in the genomes of different species) with common descent
This evidence increases our confidence that we are indeed looking at regions with shared synteny: in other words, a region in two present-day species that was once a region in the genome of their common ancestral population.
That is a fallacy. Ignoring the problems discussed above for the moment, even if evolution did make a hard prediction of shared synteny, and even if it was universally observed, that would not prove evolution. In that case, you would have a confirmed prediction. That is good, but it is not equivalent to a finding of evolution. Venema violates this scientific fundamental when he defines shared synteny as “a region in two present-day species that was once a region in the genome of their common ancestral population.” Unfortunately, affirming the consequent is not uncommon in the evolution literature.
Primeval tech continues to troll Darwinism.
Engineering and Evolution in the Microbial World
Friday, 2 June 2023
The ecosystem vs. Darwin.
The Phosphorus Cycle: Cause or Effects
Life would be impossible without phosphorus,” begins an editorial in Nature.
Present in molecules from DNA to membrane lipids to the compounds that shuttle energy in cells, it acts as an essential nutrient alongside nitrogen. Phosphorus moves through the environment in vigorous biogeochemical cycles, reflecting its chemical reactivity and intense competition by hungry organisms.
How did this bio-geo-chemical cycle begin? Scientists at the University of Cambridge are perplexed about “How life and geology worked together to forge Earth’s nutrient rich crust.” In their analysis, they see that the element phosphorus appears to have increased in the crust around the same time as the Cambrian explosion. Was one the cause or the effect of the other? It didn’t seem coincidental.
Around 500 million years ago life in the oceans rapidly diversified. In the blink of an eye — at least in geological terms — life transformed from simple, soft-bodied creatures to complex multicellular organisms with shells and skeletons.
Now, research led by the University of Cambridge has shown that the diversification of life at this time also led to a drastic change in the chemistry of Earth’s crust — the uppermost layer we walk on and, crucially, the layer which provides many of the nutrients essential to life.
They reiterate, as we’ve discussed before, that phosphorus (P) is a limiting factor on biological productivity. Unlike the other most abundant vital elements (C, H, O, N, S), P must be extracted from rocks by chemical weathering — not in its pure form, which is explosive, but as PO43- (phosphate). Microbes and plants can utilize inorganic phosphate (Pi). Then other organisms can use the phosphate-containing molecules made by them (organic phosphate, or Po).
A Biogeochemical Cycle Triggered
Craig Walton of Cambridge points out that once life became abundant in the oceans, a phosphorus recycling program could begin.
When these organisms die, most of the phosphorus is returned back into the oceans. This efficient recycling process is a key control on the amount of total phosphorus in the ocean, which in turn supports life, “It enables us to have all the life we see around us today, so understanding when this process started is really key,” said Walton.
The Oxygen Theory for the Cambrian Explosion plays into his model, although he does not explicitly say he believes oxygen caused the sudden increase in animal life. He only points out the interesting correlation.
But, all of this biological reprocessing power relies on oxygen. This is what fuels the bacteria responsible for the breakdown of dead organic material that returns phosphorus back into the oceans.
The researchers think that a surge in oxygen at around the time of the Cambrian explosion might explain why phosphorus increased in rocks. “If oxygen did increase at that time, then more oxygen may have been available to break down deep sea biomass and recycle phosphorus to shallow coastal regions,” said Walton. Moving this phosphorus back towards the land meant it was better preserved in rocks that make up the continents.“That series of changes were ultimately responsible for fuelling the activity of complex life as we know it,” said Walton.
Oxygen, therefore, is a third essential component in the phosphorus cycle.
“It’s tricky to unravel the sequence of events — whether complex life evolved in part because of increased supplies of oxygen and phosphorus to start with, or if they were in fact fully responsible for increasing availability of both, is still a controversial topic.” Walton and the team now looking to investigate the trigger for and timing of this phosphorus enrichment in the crust in more detail.
Summing up, there is a remarkable interplay of biology with two abiotic elements (oxygen and phosphorus) that sustains life on our planet. The Cambridge scientists were unable to decide which came first, how the cycle was triggered, and how things stayed in balance once the cycle was initiated.
Phosphate Balance and Management
Organisms have remarkable mechanisms for dealing with phosphate limitation, as noted here. The Nature editorial blames man for messing up the cycle by mining phosphorus for fertilizer, which often drains into the oceans, causing toxic algal blooms.
The modern phosphorus cycle has been profoundly meddled with by humans to overcome phosphorus limitation. Half of the phosphorus available to crops in agricultural soils may come from fertilizer application. Fertilizer is a limited resource — often derived from ancient rocks composed of detritus deposited beneath marine upwelling zones — and its depletion will eventually lead to problems for agriculture and other organisms that rely upon it.
In March, Science Magazine featured Dan Egan’s book about phosphorus, The Devil’s Element and a World Out of Balance, “an enjoyable, lively, and thought-provoking read” according to reviewer Robert W. Haworth, an expert on phosphorus and the environment. Wise management of this critical element will be essential, as phosphate runoff can pollute waterways and deplete soils if handled carelessly. Yet its automatic recycling through the crust and biosphere is not mentioned in the review. If the world is “out of balance” now due to human activities, how did it get into balance in the first place?
A commentary by Senjie Lin in Nature Communications explores the complexities of biological responses to phosphorus limitation, including interactions with ocean acidification, climate, and nitrogen fixation. Lin leaves more questions than answers, but notes that phytoplankton differ in their responses to pH, so much more research is needed.
Just-in-Time Delivery
One particularly interesting finding about phosphorus comes from research on fruit flies. A new organelle was found in the intestinal cells of the flies that buffers phosphate to maintain homeostasis. Described by Gemma Conroy in Nature, this “previously unknown” organelle “acts like a reservoir of phosphate, helping to regulate levels of the nutrient inside cells and triggering processes that maintain tissues when it is in short supply.”
Conroy tells how Charles Xu of Rockefeller University noticed some oval-shaped structures surrounded by multiple membranes that were being traversed by a phosphate-sensing transporter protein named PXo:
“These were quite visible, and we wondered what they were,” says Xu. When the scientists took a closer look at the mysterious structures, they saw they had several membrane layers, and the PXo protein was transporting phosphate across them. Once inside the unfamiliar organelles, the phosphate was converted to phospholipids, the main building blocks of cellular membranes.
When the fly cells were deprived of phosphate, the organelles broke apart and released the stored phospholipids into each cell, indicating that they function like reservoirs, says Xu.
His team’s paper in Nature shows microphotographs of these “PXo bodies” and describes how they store and release inorganic phosphate (Pi).
In unicellular organisms, Pi is indicative of environmental nutrient abundance and generally supports cell growth and division1. In metazoans, however, Pi availability is affected by nutrient uptake, systemic metabolism and local Pi usage, thus implicating more complex Pi signalling. In this study, we demonstrated that Pi starvation or PXo deficiency induces hyperproliferation and enterocyte differentiation in the epithelium of the Drosophila midgut, which might be a compensatory mechanism to produce more enterocytes capable of Pi absorption. Given the scarcity of knowledge about cytosolic Pi regulation in animal cells, our findings might have broad implications and open new avenues for studying Pi metabolism and signalling.
The system for just-in-time delivery of phosphates from a reservoir equipped with a sensor is reminiscent of our story about the way cells buffer and deliver heme.
Coincidences vs. Intentions
The Cambridge article says that “life and geology worked together to forge Earth’s nutrient rich crust.” From a materialist perspective, that’s a fallacy of personification. Mindless entities do not work together to forge something like a Cambrian animal body plan or a cell organelle with a sensor able to buffer phosphate for just-in-time delivery.
Scientists are generally wary of explanations that depend on lucky coincidences. In the phosphorus cycle, biology and geology are seen cooperating as to timing, triggers, balance, and homeostasis of essential parts for a functioning biosphere. These are concepts rich with purpose. If a functioning biosphere was intended, then these observational realities would make sense.
It's finally happened
Utah district bans Bible in elementary and middle schools
Why the trinity renders a definite answer to the question of JEHOVAH's identity impossible.
Matthew ch.4:11PHB"Then Yeshua said to him, “Depart Satan, for it is written: 'You shall worship THE LORD JEHOVAH your God and him(note the singular personal pronoun) ALONE shall you serve.'"
If the the object of our devotion is a mystical union of co-equals obviously their would be no single person anywhere who is entitled to exclusive devotion even if ,as some have, we make the entire union a single person,thus adding a forth person to our supposed triad. Trinitarians insists that each member of the trinity is entitled to the highest worship effectively meaning that no member of their mystifying concept including the trinity(quadrinity?) Himself is entitled to exclusive devotion
John ch.1:18ASV"No one has seen God at any time. The only begotten [h]Son, who is in the bosom of the Father, He has declared Him."
The coming to earth of our Heavenly Father's nearest and dearest Child was meant to make JEHOVAH plain to his people this is most certainly not the case with the logos of Christendom.
The fossil record trolls Darwinism some more?
Fossil Friday: How an Austrian Scientist Concocted a New Domain of Life called Gabonionta
Plenty of rights to go around?
Should We Give Nature “Rights”? A Premier Science Journal Says Yes
And yet even more primeval tech vs. Darwin
Natural Engineering in the Lifestyle of Honey Bees
Thursday, 1 June 2023
Primeval chronometers vs. Darwinism
Epigenetic Biotimer Revealed in Flowers
JEHOVAH'S Magnum opus.
Proverbs ch.8:22REB"YAHWEH had constituted me the beginning of his way, Before his works At the commencement of that time;"
Proverbs ch.8:30REB"Then I was beside him as a master worker.+
I was the one he was especially fond of+ day by day;
I rejoiced before him all the time;+ "
Micah Ch.5:2REB"Thou therefore Bethlehem Ephrathah, Though little to be among the thousands of Judah Out of thee shall Mine come forth, to be ruler in Israel,—Whose comings forth have been from of old, from the days of age-past time."
John ch.1:30NLT"He is the one I was talking about when I said, ‘A man is coming after me who is far greater than I am, for he existed long before me.’"
John ch.6:62NIV"Then what if you see the Son of Man ascend to where he was before!"
John ch.8:58NASB"Jesus said unto them, Verily, verily, I say unto you, Before Abraham was, I am(Contrast how the NASB's translators render "eimi"in harmony with the surrounding context at John ch.14:9)."
John ch.17:5NASBAnd now You, Father, glorify Me together with Yourself, with the glory which I HAD(Past tense) with(greek.para=alongside) You before the world existed."
Colossians ch.1:15-17REB"Who is an image of the unseen God, Firstborn(Prototokos) of all creation,—
16 Because in him were created all things(See proverbs 8:30) in the heavens and upon the earth, The things seen and the things unseen, Whether thrones or lordships or principalities or authorities,—They all through him and for him have been created,17 And he is before all And they all in him hold together;"
Hebrews ch.1:2NASB"[a]in these last days has spoken to us [b]in His Son, whom He appointed heir of all things, through whom(see
1John ch.1:1NASB"What was from the beginning(Grk.apo arkhe), what we have heard, what we have seen with our eyes, what we have looked at and touched with our hands, concerning the Word(Grk.logos)+ of Life"
John ch.1:1NASB"In the beginning was the Word(logos), and the Word(logos) was with (The)God(Grk.Ho Theos), and the Word(logos) was God."
John ch.1:3NASB"All things came into being through Him(See proverbs ch.8:30), and apart from Him [b]not even one thing came into being that has come into being. "
Revelation ch.3:14ASV"And to the angel of the church in Laodicea write: These things saith the Amen, the faithful and true witness, the beginning(See proverbs ch.8:22,30) of the creation of God:"