A brother in Christ and a fellow servant of Jehovah.

How do Jehovah's Witnesses view Charles T. Russell?

As Jehovah’s Witnesses today review the work that he did, the things he taught, his reason for teaching them, and the outcome, they have no doubt that Charles Taze Russell was, indeed, used by God in a special way and at a significant time.

This view is not based solely on the firm stand that Brother Russell took with regard to the ransom. It also takes into account the fact that he fearlessly rejected creeds that contained some of the foundation beliefs of Christendom, because these clashed with the inspired Scriptures. These beliefs included the doctrine of the Trinity (which had its roots in ancient Babylon and was not adopted by so-called Christians until long after Bible writing was completed) as well as the teaching that human souls are inherently immortal (which had been adopted by men who were overawed by the philosophy of Plato and which left them open to such ideas as the eternal torment of souls in hellfire). Many of Christendom’s scholars, too, know that these doctrines are not taught in the Bible, but that is not generally what their preachers say from the pulpits. In contrast, Brother Russell undertook an intensive campaign to share what the Bible actually does say with everyone who was willing to hear.

Noteworthy too is what Brother Russell did with other highly significant truths that he learned from God’s Word. He discerned that Christ would return as a glorious spirit person, invisible to human eyes. As early as 1876, he recognized that the year 1914 would mark the end of the Gentile Times. (Luke 21:24, KJ) Other Bible scholars had likewise perceived some of these things and had advocated them. But Brother Russell used all his resources to give them international publicity on a scale then unequaled by any other individual or group.

He urged others to check his writings carefully against God’s inspired Word so that they would be satisfied that what they were learning was in full harmony with it. To one who wrote a letter of inquiry, Brother Russell replied: “If it was proper for the early Christians to prove what they received from the apostles, who were and who claimed to be inspired, how much more important it is that you fully satisfy yourself that these teachings keep closely within their outline instructions and those of our Lord;—since their author claims no inspiration, but merely the guidance of the Lord, as one used of him in feeding his flock.”

Brother Russell claimed no supernatural power, no divine revelations. He did not claim credit for what he taught. He was an outstanding student of the Bible. But he explained that his remarkable understanding of the Scriptures was due to ‘the simple fact that God’s due time had come.’ He said: “If I did not speak, and no other agent could be found, the very stones would cry out.” He referred to himself as being simply like an index finger, pointing to what is stated in God’s Word.

Charles Taze Russell wanted no glory from humans. To readjust the thinking of any who were inclined to give excessive honor to him, Brother Russell wrote, in 1896: “As we have been to some extent, by the grace of God, used in the ministry of the gospel, it may not be out of place to say here what we have frequently said in private, and previously in these columns,—namely, that while we appreciate the love, sympathy, confidence and fellowship of fellow-servants and of the entire household of faith, we want no homage, no reverence, for ourselves or our writings; nor do we wish to be called Reverend or Rabbi. Nor do we wish that any should be called by our name.”

As his death neared, he did not take the view that there was nothing more to be learned, that there was no more work to be done. He had often spoken of preparing a seventh volume of Studies in the Scriptures. When asked about it before he died, he said to Menta Sturgeon, his traveling companion: “Some one else can write that.” In his will he expressed the desire that The Watch Tower continue to be published under the direction of a committee of men fully devoted to the Lord. He stated that those who would thus serve were to be men “thoroughly loyal to the doctrines of the Scriptures—especially so to the doctrine of the Ransom—that there is no acceptance with God and no salvation to eternal life except through faith in Christ and obedience to His Word and its spirit.”

Brother Russell realized that there was much work yet to be done in preaching the good news. At a question-and-answer session in Vancouver, B.C., Canada, in 1915, he was asked when Christ’s spirit-anointed followers then living could expect to receive their heavenly reward. He replied: “I do not know, but there is a great work to be done. And it will take thousands of brethren and millions in money to do it. Where these will come from I don’t know—the Lord knows his own business.” Then, in 1916, a short while before he began the speaking tour on which he died, he called A. H. Macmillan, an administrative assistant, to his office. On that occasion he said: “I am not able to carry on the work any longer, and yet there is a great work to be done.” For three hours he described to Brother Macmillan the extensive preaching work that he saw ahead, on the basis of the Scriptures. To Brother Macmillan’s objections, he replied: “This is not man’s work.”


- Jehovah’s Witnesses—Proclaimers of God’s Kingdom, 1993 WTB&TS

How's that manifest destiny thing working for you?Pros and cons.

Pakistan playing Janus with the war on terror?Pros and cons.

A clash of titans XXVI

Meals on wheels?

One man's terrorist...?Pros and cons.

A crisis of leadership among the Palestinian elite? Pros and cons.

Time for the west to mediate from the middle re: the Israeli/palestinian conflict?Pros and cons.

A clash of titans XXV

David Berlinski on becoming David Berlinski.

How David Berlinski Came to Doubt Darwin
David Berlinski 

ENV: When did you start thinking, as a critic, about Darwinian evolution? Did anythingIt was the fall of 1965. My graduate school roommate Daniel Messenger and I were ambling along Nassau Street in Princeton. We were munching the kind of wonderful Winesap apples that seem to have disappeared as a variety. I wonder why that is? Daniel's girlfriend, Sandra Petersen, was there too. Daniel was a fine philosopher and Sandra was doing a degree in classical philosophy. We walked over to Darwin's theory of evolution, living at the time in one of Princeton's back alleys.

A back alley was the right place to look for Darwin. No one in the philosophy department at Princeton had ever introduced his name into a seminar, or thought to argue that his theory was relevant to our concerns.

At Columbia College I had been given a ten minute introduction to the theory of evolution in a class otherwise devoted to comparative anatomy. The impression conveyed was that Darwin's theory was far less interesting than the details embedded in the anatomy of the Dogfish.

-- Now if you will turn to your specimens, Gentlemen...

If I had had those ten minutes to count on, Daniel had more. At Brown, he had once read Darwin's On the Origin of Species. This made him a considerable expert in my eyes. He knew what it was all about. I asked the obvious question: So is that it? 

Apparently it was.

Daniel shrugged his rounded shoulders. Someone, he said, had figured it all out.

As she always did, Sandra kept her counsel. She was fond of Daniel; she thought me an idiot.

A year later, I found myself promoted from east coast snow to west coast sunshine. And promoted to more, far more. I was an assistant professor at Stanford: That was more. And I had been given access to the splendor of northern California: That was far more. What is that wonderful line by Robert Lowell? All of life's grandeur is something with a girl in summer.

One night I was having dinner with my great friend, Daniel Gallin. At the time, he lived in San Francisco, his Delmar Street apartment high above the city. We could see the fog roll in, Nassau Street Daniel emerging briefly to offer Delmar Street Daniel the same reprise of Darwin's theory that he had once offered me. Delmar Street Daniel was doing a PhD at Berkeley with Dana Scott; he was an excellent mathematician, and an even better logician. He reserved his approval for mathematical model theory, and his admiration for Alfred Tarski.

"Can you imagine?" he would ask on reading something absurd. 

And Darwin?

Can you imagine!

*******************************************

At some time in the early 1970s, I came across the papers that Murray Eden and M.P. Schutzenberger had delivered to the 1966 Wistar Symposium, Mathematical Objections to Neo-Darwinism. I read them closely; I was impressed; and I discussed them at Columbia with Josh Kornberg, a molecular biologist, and George Pieczenik, a biochemist. Pieczenik had just finished his PhD, writing a thesis on the grammatical constraints embedded in the nucleic acids. Sympathetic to Murray's position, he had discovered two facts: The first, that the nucleic acids contain internal terminator codons and the second, that they often express very long palindromes. Josh Kornberg, on the other hand, had no intellectual capital to invest in either Murray or Marco. Not a dime, he said.

Who cares, he added?

For a while, I thought I might find a way to represent an evolutionary process in automata-theoretic terms. And for obvious reasons. The construction of a complex system demands some scheme of anticipation and deferral -- anticipation to determine where things are going, deferral to keep intermediates in reserve for later use. Finite state automata will not do; push-down storage automata are needed.

Sidney Morgenbesser accepted my paper for the Journal of Philosophy without asking for revisions. That my paper had very little to do with philosophy, he regarded as nothing more than an inconvenience. "Stick the word 'philosophy' in the title somewhere," he said. So I called my paper, "Philosophical Aspects of Molecular Biological Systems." Everyone was well satisfied, the philosophers because I was writing about biology, and the biologists because I was writing about philosophy.

It was my introduction to irrelevance, the writer's natural state.

Somewhat later, Noam Chomsky gave me a letter of introduction that allowed me to meet Marco Schutzenberger in Paris.

I've written about Chomsky and Marco in Black Mischief: Language, Life, Logic & Luck.

But this is the way it was. Darwin and I go back. He has long since moved from that scruffy back alley to something grand -- near Lake Cuomo, I believe. Still, it is lucky that we met. I might have encountered Marx instead of Darwin on Nassau Street, another one of the back-alley boys, the fall of the Berlin Wall leaving me, like Roger Kimball, dancing with ghosts. in your biography incline you to freethinking in that area?

On human cloning:looks like the fun is just getting started.

Dolly Clones Pave the Way for Human Cloning
Wesley J. Smith 

Apparently clones of the same dead sheep from which Dolly was manufactured are in good health and aging normally. From the Live Science story:

Four cloned sheep that are genetically identical to Dolly, the first cloned mammal, are still healthy even in old age, a new study found. The four sheep, which were derived from the same batch of cells as Dolly and could be considered her clone "sisters," have just reached their 9th birthday, which is equivalent to age 70 in human years, researchers who have been studying the sheep said.

A detailed study of these four sheep and nine other cloned sheep that are not related to "the Dollies" found that the animals were healthy. All of the sheep were free from many diseases commonly found in older sheep, such as diabetes and high blood pressure, the study showed.

What does this mean for the future of human cloning?

The technique, known as somatic cell nuclear transfer (SCNT) can be refined so as to permit normal mammals made in such a manner.
Human SCNT has already been done, creating embryos that were developed to the blastocyst stage (the time when stem cells can be derived).
SCNT is cloning. The result is an embryo. The question after that is how will that embryo be used.
Some human cloning apologists say that "therapeutic cloning" is different from "reproductive cloning." That's false. Those terms merely reflect different uses of the cloned embryo, the former being destroyed for research, the latter implanted in a uterus and -- as with Dolly -- brought to birth.
Bioethicists and Big Biotech support have said that human reproductive cloning should be banned until it is "safe."
Animal cloning moves that process forward as does therapeutic human cloning, since the point is to perfect the still faulty techniques needed to do in humans what is currently done in sheep.
The goals of human cloning include, but are not limited to research, learning how to genetically engineer, fetal farming, and reproductive outcomes.
Banning "reproductive cloning" is not banning cloning, but a use of a cloned embryo, in other words, a phony ban intended to fool people.
The time to outlaw human cloning is now -- meaning all human SCNT, regardless of the use to which the embryo will be put. If we wait until the sector perfects its techniques, it will be too late.

Will we? Not a chance. The media are asleep and/or active boosters of Big Biotech and Congress is safely in their campaign donation-paid special interest pockets.


There will be consequences.

On S.E.T.I or still waiting by the phone.

After Fifty Years of Searching for ETs, Materialists Won't Take No for an Answer
Evolution News & Views

Ideas have consequences. If your idea is that life on Earth is nothing special, it follows that life should be plentiful in the cosmos. If you believe life and intelligence are accidental byproducts of matter and energy, you would probably want to communicate with others like us -- that is, unless (like Stephen Hawking) you think aliens might be as dangerous as we are to each other. Optimists in the SETI community outnumber pessimists. So they search.

And search. Half a century later, no signal has been detected. Astrobiologists (those who look for any kind of life beyond Earth, intelligent or not) can't even find microbes within our own solar system.

People are certainly free to pursue their own dreams. SETI only gets controversial when taxpayers have to pay for it. Search enthusiasts are chagrined that astrobiology gets NASA money, but they do not. Ever since Congress laughed it out of chambers with jokes about little green men, SETI advocates have had to raise their own money. With help from billionaires like Paul Allen and Yuri Milner, the search has continued. But even with technological innovations allowing the monitoring of a million channels simultaneously (far beyond Frank Drake's single-channel search of two stars in 1960), no signal of intelligent origin has yet turned up.

The true believers have one point in their favor; the search space is too vast to expect success in just 56 years, given our current search technology. But other possibilities exist. Life is rare; we are alone; or, perhaps, alien life is so different from what we know, we have no idea how to find it. From another direction, molecular biologists have continued to uncover unexpected complexity in even the simplest life, leading some to conclude life is rare.

These and other ideas are discussed in a paper by Nathalie A. Cabrol in the journal Astrobiology. A senior research scientist for the SETI Institute, Cabrol feels it's time for a major new interdisciplinary effort to look for intelligent aliens (see also Elizabeth Howell's write-up at Space.com, with video clip, "Are We Alone in the Universe?"). To succeed, Cabrol argues, we will need to expand our search to "life as we do not know it."

The evolutionary pathways that lead to complex life on Earth strongly suggest that advanced life as we know it may be rare in the Universe and unlikely to be in a state of advancement that is temporally synchronous with us. However, that does not mean that other types of advanced intelligences are as rare. Limiting our search to something we know and can de facto comprehend is, probabilistically, a constraining proposition, one that leaves no room for an epistemological and scientific foundation to explore alternate hypotheses. To find ET, we must expand our minds beyond a deeply rooted Earth-centric perspective and reevaluate concepts that are taken for granted. [Emphasis added; italics in the original.]
One way we can expand our minds is to play Mr. Spock and do a kind of "mind meld" with the aliens, using imagination. Here, Cabrol runs the risk of eliciting more Congressional guffaws:

Rather than constraining the search, SETI efforts must involve the most expansive exploration tool kit possible. If we unbind our minds, it should not matter whether ET looks or thinks like us, has a logic that makes any sense to us, or uses familiar technology for interstellar communication. ET is likely to be very different from us and completely alien to our evolutionary processes and thought processes, which may be deeply connected (see Section 5.2.3). Ultimately, to find aliens, we must become the aliens and understand the many ways they could manifest themselves in their environment and communicate their presence.
Such an intellectual framework not only moves the Drake equation forward toward the existence of drastically different probabilistic civilizations, it also brings us to consider alternate evolutionary pathways, including life as we do not know it and do not yet understand. Further, such a framework allows us to look at evolutionary pathways in our own biosphere and question the emergence of complex, intelligent life with a different set of eyes. For that to happen, we must conceptualize something we do not know, which can be approached in a number of different ways. One is by trying to access unknown concepts and archetypes that are literally alien to us (i.e., not part of our own evolutionary heritage) through imagination and discourse. This is what science fiction attempts to do in its depictions of alien worlds and civilizations. Not surprisingly, this process results in more or less elaborate versions of ourselves, since these representations are generated by neural systems wired to our own planetary environment. To conceptualize a different type of life, we have to step out of our brains. [Italics in the original.]

For those of us preferring to keep inside our brains, we see that ET can become an obsession to believers, like Richard Dreyfuss in Close Encounters, who would not take no for an answer. The silence does not mean aliens are not out there. They are just so alien we can't use the scientific method; we have to imagine them. We have to become them. Whether Cabrol's appeal will rouse support remains to be seen.

Cabrol is not alone. Fact-challenged as it is, SETI is a running theme in the popular science media. And there's a lot of money being thrown at it.

Ian O'Neill from Discovery News reports on a "targeted SETI" approach, using the Allen Telescope Array to listen for signals from candidate planets discovered by the Kepler Spacecraft. (Space.com)

China has just completed the world's largest radio telescope, in hopes of "finding new worlds and alien life." Though built for traditional science, "it can also eavesdrop on distant worlds to search for intelligent life," says Elias Brinks at The Conversation.

English scientists are practicing searches for exotic life deep in a salt mine, hoping to transfer what they learn to searches for life underground on Mars. (New Scientist)

New Scientist reports that several scientists are upset that NASA is not doing enough to search for alien life. They want more attention on the search in the Mars rover programs and the James Webb Space Telescope goals. Why? "As well as many other scientists who support the search for life elsewhere, it tops the lists of the most exciting questions driving science today for people outside the field," Shannon Hall writes.

At Live Science, Mindy Weisberger explores the fascination with "little green men" by examining the historical roots of the familiar icon that has persisted for decades.

Last month, a Cornell student, Evan Solomonides, presented "A Probabilistic Analysis of the Fermi Paradox," excusing the silence on the "Mediocrity Principle" wrongly attributed to Copernicus (see The Privileged Planet for refutation). Solomonides was inspired by Carl Sagan's view that humans are nothing special in the vastness of space. With that as his guide, he calculated (with no data on aliens) that it will be 1,500 years before aliens contact us. (Cornell Chronicle)

To appreciate how scientifically groundless these speculations are, imagine for a moment that a cult of religious fanatics controlled the reins of science. Convinced that ghosts are real, they search diligently for decades, creating more and more elaborate devices to find them. They refuse to take non-detection as an answer. Speculation joins imagination to explain why they are not found. Some of the true believers propose becoming ghosts to understand them. Others propose that ghosts are so clever, they are purposely concealing themselves. Another group speculates that they are so weird, we cannot even begin to imagine what they are like. Go ahead; use all the SETI speculations for this scenario. Even if these searches understood quantum physics and relativity and used sophisticated engineering, would that rationalize the ideology?

In the history of science, some searches for "occult phenomena" (referring not to spiritual entities, but to suspected-but-as-yet-unobserved realities) have borne fruit; recent examples include the Higgs Boson and gravitational waves. Other searches have not (caloric, phlogiston, alchemy). The search for dark matter is currently in crisis, failing the most sensitive search to date (Space.com). At some point, a quest must acquire data to justify its claim to be scientific.

Despite continued failures, SETI is unlikely to cave anytime soon. Its motivations are too deeply grounded in evolutionary ideology. The believers think it too incredible to imagine humans as unique or exceptional in such a vast universe. To be sure, this "gut feeling" extends outside evolutionary circles. But where is the evidence? While the complexity of life and the uniqueness of Earth have become more apparent, the aliens have remained silent.

Here are two points to note about this undying fascination with aliens in the SETI community and in the science media. One is its dependency on the materialist, Darwinian worldview. Cabrol's paper contains over a hundrew references to evolution in the text and references.


The second is the inherent inconsistency of this perspective. The SETI community is almost entirely composed of people who attack ID as unscientific. Yet over and over we see them using a framework of intelligent design, though not by that name, in their searches! SETI rests on the premise that intentional, purposeful signals can be distinguished from natural processes. They speak effusively about communication channels, signals, and intentions of beings that they don't even know exist. Remember this next time someone levels the charge against ID that it points to a designer outside of science.

Why appeals to common design re:homology are not a cop out.

Why Similarities Do Not Prove the Absence of Design
Granville Sewell 

The idea that the "survival of the fittest" could produce all the magnificent species on Earth, and human brains and human consciousness, is so unreasonable -- how did such an idea ever become so widely accepted in the scientific world? There are two reasons.

First, science has been so successful explaining other phenomena in Nature that -- understandably -- today's scientist has come to expect that nothing can escape the explanatory power of his science. And Darwinism, as far-fetched as it is, is the best "scientific" theory he can come up with for evolution. As microbiologist René Dubos puts it in The Torch of Life, "[Darwinism's] real strength is that however implausible it may appear to its opponents, they do not have a more plausible one to offer in its place." But we have already seen why evolution is a very different and much more difficult problem than others solved by science, and why it requires a very different type of explanation.

Second, for most modern minds, the similarities between species not only prove common descent, they prove that evolution was the result of entirely natural causes, even in the absence of any evidence that natural selection can explain the major steps of evolution. The argument is basically, "This doesn't look like the way God would have created things," an argument used frequently by Darwin in the Origin of Species. But if the history of life does not give the appearance of creation by magic wand, it does look very much like the way we humans create things, through testing and improvements.

In fact, the fossil record does not even support the idea that new organs and new systems of organs arose gradually. Instead, new orders, classes, and phyla consistently appear suddenly. For example, Harvard paleontologist George Gaylord Simpson writes:

It is a feature of the known fossil record that most taxa appear abruptly. They are not, as a rule, led up to by a sequence of almost imperceptibly changing forerunners such as Darwin believed should be usual in evolution.... This phenomenon becomes more universal and more intense as the hierarchy of categories is ascended. Gaps among known species are sporadic and often small. Gaps among known orders, classes and phyla are systematic and almost always large. These peculiarities of the record pose one of the most important theoretical problems in the whole history of life: Is the sudden appearance of higher categories a phenomenon of evolution or of the record only, due to sampling bias and other inadequacies?
Actually, if we did see the gradual development of new orders, classes and phyla, that would be as difficult to explain using natural selection as their sudden appearance. How could natural selection guide the development of the new organs and entire new systems of interdependent organs which gave rise to new orders, classes, and phyla, through their initial useless stages, during which they provide no selective advantage? French biologist Jean Rostand, in A Biologist's View, wrote:

It does not seem strictly impossible that mutations should have introduced into the animal kingdom the differences which exist between one species and the next... [H]ence it is very tempting to lay also at their door the differences between classes, families and orders, and, in short, the whole of evolution. But it is obvious that such an extrapolation involves the gratuitous attribution to the mutations of the past of a magnitude and power of innovation much greater than is shown by those of today.
Rostand says, nevertheless, "However obscure the causes of evolution appear to me to be, I do not doubt for a moment that they are entirely natural."

We see this same pattern, of large gaps where major new features appear, in the history of human technology. (And in software development, as discussed in my Mathematical Intelligencer article "A Mathematician's View of Evolution.") For example, if some future paleontologist were to unearth two species of Volkswagens, he might find it plausible that one evolved gradually from the other. He might find the lack of gradual transitions between automobile families more problematic, for example, in the transition from mechanical to hydraulic brake systems, or from manual to automatic transmissions, or from steam engines to internal combustion engines. But if he thought about what gradual transitions would look like, he would understand why they didn't exist: There is no way to transition gradually from a steam engine to an internal combustion engine, for example, without the development of new, but not yet useful, features. He would be even more puzzled by the huge differences between the bicycle and motor vehicle phyla, or between the boat and airplane phyla. But heaven help us when he uncovers motorcycles and hovercraft, the discovery of these "missing links" would be hailed in all our newspapers as final proof that all forms of transportation arose gradually from a common ancestor, without design.

The similarities between the history of life and the history of technology go even deeper. Although the similarities between species in the same branch of the evolutionary "tree" may suggest common descent, similarities (even genetic similarities) also frequently arise independently in distant branches, where they cannot be explained by common descent. For example, in their Nature Encyclopedia of Life Sciences article on carnivorous plants, Wolf-Ekkehard Lönnig and Heinz-Albert Becker note that

...carnivory in plants must have arisen several times independently of each other... the pitchers might have arisen seven times separately, adhesive traps at least four times, snap traps two times and suction traps possibly also two times.... The independent origin of complex synorganized structures, which are often anatomically and physiologically very similar to each other, appears to be intrinsically unlikely to many authors so that they have tried to avoid the hypothesis of convergence as far as possible.
"Convergence" suggests common design rather than common descent: the probability of similar designs arising independently through random processes is very small, but a designer could, of course, take a good design and apply it several times in different places, to unrelated species. Convergence is a phenomenon often seen in the development of human technology. For example, Ford automobiles and Boeing jets may simultaneously evolve similar new GPS systems.

So if the history of life looks like the way humans, the only other known intelligent beings in the universe, design things -- through careful planning, testing, and improvements -- why is that an argument against design? Somehow we got the idea that nature's designer shouldn't need to get involved in the details, and so should be able to create anything from scratch, using a magic wand. But no matter how intelligent a designer is, he still has to get involved in the details -- that's what design is!

Some people counter by saying that of course cars cannot evolve like animals, because they cannot reproduce, so there are no "variations" for natural selection to work with. But the main point here is not about natural selection -- it is only that similarities between "species" (of cars or animals) do not prove the absence of design.


However, even though it is irrelevant to my main point here, let's look at the argument that evolution is easier to explain if there is reproduction. Is that really so? If cars were able to reproduce themselves almost perfectly (the copies even retaining the ability to reproduce themselves!), with occasional minor errors, would that make the evolution of cars easier to explain without design, than if individual cars experienced slight changes or improvements directly, though rust or crashes or other natural causes? We are so used to seeing animals make nearly perfect copies of themselves that we dismiss this as just another "natural" process; but if we saw cars giving birth to cars, maybe we would realize that this would actually make automobile evolution even more amazing and more difficult to explain without design.

Darwinism Vs. the real world XXX

The Neuromuscular System: Your Body's Balancing Act
Howard Glicksman 

Editor's note: Physicians have a special place among the thinkers who have elaborated the argument for intelligent design. Perhaps that's because, more than evolutionary biologists, they are familiar with the challenges of maintaining a functioning complex system, the human body. With that in mind, Evolution News is delighted to offer this series, "The Designed Body." For the complete series, see here. Dr. Glicksman practices palliative medicine for a hospice organization.

The nerves and muscles of our body allow us not only to breathe, but also to move around and manipulate things. But how do they do it? In my last I article showed that nerve cells (neurons) and muscle cells (myocytes) are excitable. This means that when adequately stimulated, they depolarize. By letting large amounts of Na+ ions enter, they cause the plasma membrane to go from being negatively charged to positively charged. Depolarization triggers large amounts of Ca++ ions to enter the cell, causing the neuron to release its neurotransmitter and the myocyte to contract.

The nervous system is set up like a military operation. Reconnaissance from sensory neurons within the peripheral nerves is sent to and organized by the spinal cord and transmitted to the brain. The brain, acting as headquarters, analyzes the sensory information, makes decisions, and sends out orders. The orders travel to and are organized by the spinal cord and sent through the motor neurons within the peripheral nerves. The messages tell the muscles to contract, which results in controlled and purposeful movement. The success of a military operation is dependent on having good information about the enemy and one's own troops. Let's look at some of the ways the body acquires the information it needs about its external and internal environment so it can know what to do and act accordingly.

Everyone knows that an odometer measures distance and a speedometer measures velocity. Each device is essentially a sensory transducer with a mechanism in place that enables it to sense a physical phenomenon and convert it into useful information. We have seen that the body has a whole host of sensory transducers, which provide the information necessary to maintain its internal environment. They are divided into three different categories: chemoreceptors, which respond to chemicals, like oxygen, glucose and calcium; mechanoreceptors, which respond to motion and stretch, like the baroreceptors in the walls of the arteries leading to the brain that monitor blood pressure; and physical sensors, which respond to natural phenomena, like the thermoreceptors in the hypothalamus that detect core temperature.

The skin not only protects the body from infection and injury. It also provides sensory information about its immediate surroundings. The skin has different sensory receptors that can detect light touch, pressure, motion, vibration, and temperature. It has pain receptors that react to chemicals related to nearby cell injury. They also react to too much pressure or motion and extreme temperatures. Adequate stimulation of any one of these sensory receptors causes the associated neuron to depolarize and release its neurotransmitter. The neurotransmitter then depolarizes a nearby connecting neuron in a cascade that transmits the message all the way to the brain, usually in the sensory region of the cerebral cortex.

In addition to the skin, which provides sensory information about the body's external environment, there are pain and mechanoreceptors in and around the joints, ligaments, and deep soft tissues. These, in addition to chemoreceptors within the major organs, provide sensory information about the body's internal environment. Although we are aware of many of the sensations caused by our external and internal environment, one set, the proprioceptors, acts unconsciously and without them life would be impossible.

Proprioception involves joint position awareness and kinesthesia, or the awareness of joint and limb movement through muscular effort. The proprioceptors tell the central nervous system about muscle length, joint position, and limb movement. If the body had no way of knowing what its muscles and joints were doing and where its bones were located in space, then how could it control its position and movements? In addition to the mechanoreceptors in and around the joints, the two main proprioceptors are the muscle spindles and the Golgi tendon organs, which provide sensory information on joint position and muscle movement.

The Golgi tendon organ joins the muscle to the tendon as it is attached on one end to the muscle fibers and on the other end to the tendon. Because it is directly connected, in series, to the muscle and the tendon, the Golgi tendon organ is sensitive to the degree of tension applied by muscle contraction.

An increase in tension causes the Golgi tendon organs to increase their impulses to the spinal cord, causing an immediate reflex inhibition of muscle contraction and a reduction in tension. This explains one of the important functions of the Golgi tendon organs: preventing muscle injury and tendon rupture by causing automatic muscle relaxation in the presence of dangerously high levels of tension.

Conversely, a decrease in tension causes the Golgi tendon organs to decrease their impulses to the spinal cord, which results in an immediate reflex reduction in inhibition causing an increase in muscle contraction. This explains another important function of the Golgi tendon organs, which is to help the body maintain its posture while performing goal directed activities.

Muscle fatigue, with its resulting diminished contraction, can lead to inadvertent falling or unexpected changes in position. But the information sent by the Golgi tendon organs to the spinal cord reflexively makes the flagging muscles contract more to allow the body to maintain its posture. Clearly, without the Golgi tendon organs to tell the central nervous system what's going on at the level of where the muscle attaches to the tendon, our ability to move around would be impossible.

Muscle spindles are sensory organs consisting of modified muscle fibers positioned in between and parallel to the skeletal muscle fibers, allowing them to compare their respective lengths. Since each skeletal muscle is usually attached to two different bones across a joint, its length also determines the angle of the joint and its position.

For example, when the elbow is fully extended to zero degrees, the biceps are at their greatest length and the triceps are at their shortest. In contrast, when the elbow is fully flexed at about 160 degrees, the biceps are at their shortest length and the triceps are at their greatest. When the angle of the elbow is in between, at 80 degrees, so too are the lengths of the biceps and the triceps. This demonstrates one of the functions of the muscle spindles, which is to provide the central nervous system with information about the length of each skeletal muscle and the angle and position of its associated joint.

If the skeletal muscle fibers are longer than the muscle spindles (an indication of being stretched) the muscle spindles react by sending more impulses to the spinal cord, reflexively causing muscle contraction. Conversely, if the skeletal muscle fibers are shorter than the muscle spindles (an indication of muscle contraction) the muscle spindles react by sending less impulses to the spinal cord which reflexively results in muscle relaxation. This demonstrates another important function of the muscle spindles. Like the Golgi tendon organs, they help the body maintain its posture and position in space while performing purposeful movements.

In a static situation, such as carrying a load in front of the body, it is easy to understand how the muscle spindles maintain position through changes in muscle function. In this setting, the elbows must be maintained at about ninety degrees by the combined actions of the biceps and triceps. During this activity, stretching (lengthening) of the biceps, due to muscle fatigue, will at the same time cause a shortening (contraction) of the triceps. If this is not corrected quickly the angle of the elbow will decrease and allow gravity to take more effect which may cause the load to be dropped.

To prevent this from happening, the muscle spindles in the biceps detect the lengthening and send more messages to the spinal cord, reflexively causing an increase in the contraction of the biceps. This maintains the angle of the elbow at ninety degrees so as to not drop the load. At the same time, the muscle spindles in the triceps detect the shortening of its muscle fibers and send out fewer messages to the spinal cord, reflexively resulting in relaxation of the triceps so that the ninety-degree elbow angle is maintained.

Clinical experience with diabetics and others who suffer from sensory nerve malfunction indicates that without any one of the above-mentioned sensory devices, it would have been impossible for our earliest ancestors to survive. Evolutionary biologists must explain how each of them came about and their presence in the precise locations where they are needed in addition to how intermediate life forms could have survived throughout this developmental process.


Next time we will look at the special sense of vision and see what it requires.

Yellow journalism will be the death of Britain?:Pros and cons.

Demythifying peer review II

The Hoax on Us
Drivel, Fraud & Gibberish in Scientific Papers
by Denyse O'Leary

An entertaining but revealing development in science culture in recent years has been the intentionally nonsensical academic paper. Earlier this year, political scientist Peter Dreier admitted at Prospect that his abstract for a panel of six years ago, "On the Absence of Absences," was "academic drivel":

I tried, as best I could within the limits of my own vocabulary, to write something that had many big words but which made no sense whatsoever. I not only wanted to see if I could fool the panel organizers and get my paper accepted. . . .1

Well, not only was it accepted, but he was also invited to join fellow academics in Tokyo at the annual international conference of the Society for Social Studies of Science.


Sokal & His Imitators

The hoax journal paper genre was started, as Dreier explains, by New York University physicist Alan Sokal in 1996. Sokal aimed to skewer the postmodern dogma that facts, even in mathematics and physics, are merely a social construct. He submitted an article to Social Text, a postmodern cultural studies journal, that, "shorn of its intentionally outrageous jargon, essentially made the claim that gravity was in the mind of the beholder." The paper, "Transgressing the Boundaries: Towards a Transformative Hermeneutics of Quantum Gravity," was published in the Spring/Summer 1996 issue of the journal. Writes Dreier:

As soon as it was published, Sokal fessed up in another journal (Lingua Franca, May 1996), revealing that his article was a sham, describing it as "a pastiche of Left-wing cant, fawning references, grandiose quotations, and outright nonsense . . . structured around the silliest quotations [by postmodernist academics] he could find about mathematics and physics."2

Sokal has had many imitators since, a disquieting number of whom have been successful. One entertaining 2015 hoax purportedly showed that boo-boo kisses from mommy did not help heal children's scrapes and recommended "a moratorium on the practice." Other entries don't sound quite so cute, however.

For example, in 2005, MIT researchers developed software they called SCIgen, which "randomly combines strings of words to produce fake computer-science papers." Their aim was to demonstrate that "conferences would accept meaningless papers."3 That was no idle concern. In 2014, computer scientist Cyril Labbé catalogued 120 computer-generated "gibberish" papers that had been published as conference proceedings in the five years between 2008 and 2013 alone. Sixteen papers had appeared in publications of the well-regarded science publisher Springer, and more than 100 were published by the Institute of Electrical and Electronic Engineers. All the papers had to be removed from the relevant databases.

Once discovered, hoax papers can sometimes be retracted with little fuss, but other times the matter doesn't end well. In a very recent case, the authors of a hoax paper about death-camp guard dogs had intended to satirize postmodern attempts to "interpret historical events through the perspective of affected animals." Unfortunately, the authors failed to let the journal or their readers in on the joke. The paper was retracted with some pointed criticism.4

Along with hoax papers, there has been an increase in fraudulent journal papers as well,5 but here we should recognize a distinction: frauds are not the same thing as hoaxes. Piltdown Man and the feathered dinosaur ("Piltdown Chicken"), to cite two concrete examples, were frauds. The fraudster needs the world to believe—and go on believing—the fraud. The hoaxer, by contrast, delights in the moment he can reveal the truth, for that is the point of the exercise.

Left-Wing Bias Paints the Target

Both fraudulent and hoax papers riff off the needless complexity of today's academic prose. Granted, lay readers are often going to be baffled by forbidding but essential technical terms in a research paper. But papers that baffle everyone—even those in the field—while sounding profound are a different matter. Such papers can be seen as resulting from the postmodern invasion of the sciences by nihilist philosophies. Indeed, wags now offer tongue-in-cheek directions for perpetrating a science hoax, and explain how to construct a gibberish paper that gets accepted by journals.5 Perhaps many journals find it easier just to accept a few such papers than to confront the troubling reality they represent: that words don't need to mean anything to be accepted in their discipline.

Social science is especially hard-hit these days; one psychologist described it as "riddled with flaky research and questionable theories."6 There is a surprisingly broad consensus about the cause—that is, everyone from Michael Shermer to Uncommon Descent agrees on it—namely, that the field's overwhelmingly progressive-left bias makes it an easy mark for both hoaxes and frauds.7

It also makes it an easy target for a third category of problem paper that is neither a hoax nor a fraud exactly: the nonsense paper that may well be believed by its authors. Examples of these include the widely cited "positivity ratio" in psychology, which was assessed as "entirely unfounded" in 2013,8 and the recent, apparently serious attempt to "feminize" melting glaciers.9

This sort of thing should come as no surprise. Monochromatic bias exposes a community to greater risk because few of its members even notice a hoax, fraud, or nonsense thesis that passes their bias filter. Usually, the person to whom it doesn't sound right has different commitments and life experiences, and he or she is the one motivated to investigate.

Ironically, many defenders of the status quo in recent years have claimed to be "scared to death of the anti-science lobby."10 Their worries are misplaced. It's actually science that is coming to get them. Soon. •

Notes
1. Peter Dreier, "Academic Drivel Report," Prospect (Feb. 22, 2016): http://bit.ly/1QeFT8Q.
2. Ibid.
3. Nature News (Feb. 24, 2014): nature.com/news/publishers-withdraw-more-than-120-gibberish-papers-1.14763.
3. "Death camp dog satire retracted when German journal wasn't in on joke," Retraction Watch (Mar. 1, 2016): http://bit.ly/1Tt5vEU.
4. Ibid.
5. Adam Ruben, "Forging a Head," Science (Apr. 22, 2011): http://bit.ly/21ZSNCF; Rob Sheldon, "How, exactly, to construct a gibberish paper that gets accepted by journals," Uncommon Descent (Mar. 6, 2014): http://bit.ly/1XcVycU.
6. Claire Lehmann, "How a rebellious scientist uncovered the surprising truth about stereotypes," Quillette (Dec. 4, 2015): http://bit.ly/1SExNbD.
7. Michael Shermer, "Is Social Science Politically Biased? Political bias troubles the academy," Scientific American (Mar. 1, 2016): scientificamerican.com/article/is-social-science-politically-biased.
8. The Scientist (Aug. 7, 2013): the-scientist.com/?articles.view/articleNo/36910/title/-Positivity-Ratio--Debunked.
9. "As glaciers melt, more voices in research are needed," Around the O (Feb. 25, 2016): http://bit.ly/1QW7efz.
10. Robin McKie, "Attacks paid for by big business are 'driving science into a dark era,'" The Guardian (Feb. 19, 2012): http://bit.ly/1nwMgfE.

Birds in the dock for Design

How Hummingbirds Avoid Collisions
Evolution News & Views

Who doesn't enjoy watching hummingbirds through the window at their backyard feeder? These amazing birds, zipping to and fro in all directions at stunning velocity, never seem to crash. Intrigued by their flight prowess, Canadian scientists decided to look into how they do it. They learned something new and unique about the tiny birds' strategy for collision-free navigation.


To make controlled observations of hummingbird paths, the team from the University of British Columbia built a flight simulator consisting of a long box 5.5 meters long, lined with eight cameras. On the side walls, they could project images of vertical and horizontal lines of various widths, and control their motions. Then they caught 18 wild hummingbirds, kept them separate from one another, and trained them to fly the tunnel toward a feeder. While projecting a wide variety of patterns on the walls, they filmed 3,100 flights by the birds.



The results are published in the Proceedings of the National Academy of Sciences (PNAS). New Scientist says:

Hummingbirds have a unique collision avoidance system built into their brains that allows them to perform high-speed aerobatics in safety.
The super-agile birds, whose wings beat up to 70 times a second, can hover, fly backwards, and whizz through dense vegetation at more than 50 kilometres per hour.

How they manage to avoid potentially fatal crashes has remained a mystery until now. Researchers in Canada conducted a series of experiments which showed that the birds process visual information differently from other animals. [Emphasis added.]

Here's what the team expected. Based on earlier studies with insects, they thought that birds would respond to moving stripes on the side walls. The paper states:

Information about self-motion and obstacles in the environment is encoded by optic flow, the movement of images on the eye. Decades of research have revealed that flying insects control speed, altitude, and trajectory by a simple strategy of maintaining or balancing the translational velocity of images on the eyes, known as pattern velocity. It has been proposed that birds may use a similar algorithm but this hypothesis has not been tested directly.
To their surprise, the scientists found that hummingbirds use a different strategy. They don't seem to be affected by pattern velocity, at least when seeing vertical stripes pass by along the walls (known as "nasal-to-temporal pattern velocity"). One would think that the speed of moving bars in their peripheral vision (i.e., the optic flow), would make them speed up or slow down as they approached the feeder; this is known as the "telegraph pole effect," familiar to drivers who can gauge their speed by the passing of telephone poles. But no matter how they varied the speed of the vertical stripes, it didn't seem to matter to the birds. New Scientist explains:

When the scientists simulated the "telegraph poles effect" with vertical moving stripes, the hummingbirds did not react. Instead, they appeared to rely on the size of objects to determine distance, steering away from the stripes as they grew larger.
"When objects grow in size, it can indicate how much time there is until they collide even without knowing the actual size of the object," says Dakin. "Perhaps this strategy allows birds to more precisely avoid collisions over the very wide range of flight speeds they use."

It's not that the birds were incapable of responding to the speed of the moving bars. When horizontal bars were projected moving up or down, the birds did respond by varying their altitude, probably using the information to gauge their risk of hitting the ground. But for preventing collision with the feeder, they appeared to rely mainly on the increasing vertical size of the target.

Further tests confirmed their findings. Instead of stripes, they tried projecting moving dots. They tested many combinations of dots, stripes, stripe orientations and stripe motions. The secret became clear: expansion of an object in any part of the field of view was the bird's cue to respond. They would slow down or steer away from anything that grew in size vertically.

Collectively, our findings suggest that birds control forward flight by monitoring changes in the vertical axis: specifically, the height of features and vertical pattern velocity. This finding is consistent with other laboratory studies showing that flying birds rapidly stabilize key features in their visual field. In nature, collisions may be avoided by monitoring changes in the apparent size of features, such as trees and branches, as well as changes in the vertical position of those features. Although our experiments focused on manipulating a limited number of cues, we do not suggest that these represent the only visual guidance strategies used by birds.
Now apply this to a confusing, dynamic tangle of branches, leaves, flowers, and objects that hummingbirds must face in their natural environments. The strategy allows them to quickly zero in on the pertinent optic flow information to avoid collisions. Moving at 50 km/hour, hummingbirds must be quick! This programmed strategy avoids TMI (too much information), giving them only what they need at the moment, even though their brains are perfectly capable of gathering and processing all the information in the visual field.

It makes sense that birds, being much larger than insects, would use a different strategy for collision avoidance. It appears that the strategy is common to birds. Previous tests with budgerigars (the pet parakeets) showed similar responses. Now see what a large goshawk has to deal with in its flight through a tangled forest!





The scientists realize that the behaviors must relate somehow to actual nerve impulses:

Neurons that compute expansion have been identified in the nucleus rotundus of the pigeon brain, part of the tectofugal pathway.... These cues can inform an animal about the nearness in time of an impending collision, triggering an appropriately timed response without knowledge of the true size or distance of the approaching object. It was recently discovered that the zebra finch nucleus rotundus also contains cells that respond during simulated flight if an approaching feature is located at the point of expansion, suggesting that the tectofugal pathway may also be involved in flight control.
Flight control. That's design. Understandably, the scientists did not speculate about how flight control systems might have evolved. Spinning a "narrative gloss" on the findings would have dubious value.

On the contrary, you can certainly appreciate that the knowledge gained by investigation of "flight control" in hummingbirds might improve the design of drones, now that "drone racing" is becoming one of the hottest new sports. Look at this:




As you watch the man-made racing drones suffer "spectacular crashes" in their "daring aerial maneuvers," then realize that hummingbirds already had collision avoidance figured out, you can't help but remember Paul Nelson's quip in Flight: The Genius of Birds, "If something works, it's not happening by accident."

The undeniable logic of the case for design II

If You Could Get a Critic to Read Just One Book about Intelligent Design, It Might be Undeniable
David Klinghoffer

Following the evolution debate for me has been a revelation about human nature, among other things, showing as it does how fiercely resistant the mind is to considering other intellectual frameworks. The library of books that make the argument for ID is rich and multifaceted. Yet one of the perennial laments of the ID proponent is that we have a hard time getting our critics, whether in the science or media world, to read any of this literature.

They are much more likely to content themselves with a quick skim of the woefully misleading Wikipedia page, followed by the one word dismissal, "creationist." Sometimes, then, you can't help daydreaming: If you could give a critic just one book on ID with the assurance that he or she would actually read it, what would that book be?

It's a tough question. Certainly Doug Axe's new book, Undeniable:  Undeniable: How Biology Confirms Our Intuition That Life Is Designed, would be a contender for its concision, accessibility, rigor, and passion. I've already shared with you what some open-minded scientists have said about the book (see here  and  here). Here's more from a diverse and distinguished readership.

Undeniable speaks to everyone, and who would know better about that than a New York Times bestselling novelist like Dean Koontz? Says Mr. Koontz:

Great scientists are as much artists as scientists. Enchanted by the beauty of the world, they see through ideologies to facts. In this engaging book, with facts and humility and humor and reason, Axe uses "common science" to consider the biggest mystery: To what or to whom do we owe our existence? I greatly enjoyed it.

It speaks to ultimate questions of origins, from the perspective of science. And who would know better about that than physicist Gerald Schroeder, author of The Science of God:

So often we read secondary accounts of the intelligence that lurks behind the wonders of life. In Undeniable we are privy to a first-hand account of the evidence for intelligence, and also the painful professional cost of swimming against the flow of an accepted, but un-proven, truth. A must-read.

Yes, though newly published, it's already on its way to being recognized as an ID classic. And who would know better about that than an icon and founder of the intelligent design movement, Phillip E. Johnson, Professor Emeritus of Law at U.C. Berkeley and author of Darwin on Trial? Says M. Johnson:

Douglas Axe's Undeniable is bold, insightful and world-changing. It's also a joy to read. I recommend it highly!

Finally, in case you missed it already, Dr. Axe explains the science behind our intuition of design in nature. Not all intuitions are reliable, but this one reflects what Axe calls "common science." Here, then, is still another scientist, biologist Donald Ewert, Director of Research at the Hough Ear Institute and former Wistar Institute Research Scientist. Says Dr. Ewert:

Life begs for an explanation. Written from point of view of a molecular biologist Undeniable makes a compelling case based on current research and human reasoning that living organisms were designed by an intelligent agent. Axe delivers a decisive blow to the foundations of materialistic explanations of the origin and diversity of life's forms, explanations that have dominated biology for the past two hundred years years. He demonstrates an informed grasp of the current scientific and philosophical information that he communicates in an interesting style that can be understood by most laymen. Undeniable will change the way you think about the living world.


That's some very impressive praise. Surely Undeniable belongs in your ID library.

RNA first theory on the rocks

A Chilling Origin of Life Scenario
Evolution News & Views

The most popular of the Origin of Life (OOL) models is the RNA-first world. RNA can have catalytic properties similar to proteins (enzymes) and are thus called ribozymes. RNA or some form of pre-RNA is an attractive early earth molecule and possible progenitor to early life because, unlike the chicken-and-egg problem with proteins and DNA, theoretically, RNA replication can be completely self-contained. In fact, in January 2009 Nature reported on the synthesis of a self-replicating RNA molecule capable of catalyzing its own replication. See Casey Luskin's report here.
There are several problems with the RNA-first model (See here for a short discussion on some problems with RNA, and see Chapter 14 in Signature in the Cell) not the least of which is how difficult RNA is to synthesize. However, two of the major problems that OOL researchers face are the inherent instability of RNA (a much less stable molecule than DNA) and the dilute reaction conditions that were likely on the early earth. A recent Nature Communications proposes a hypothesis that addresses these problems. The authors propose that perhaps these early earth RNA reactions occurred in ice.

The authors began with 18R RNA polymerase ribozyme because of its similarity to probable early earth RNA and brought their reaction solution to the eutectic phase (a specific temperature range for a particular solution) to see whether RNA replication occurs. Although the authors admit that the reaction is slowed down considerably, the sub-zero temperature stabilizes the products, and the formation of ice crystals concentrates the reactants. Overall, they obtained products in the range of 32 to 41 nucleotides, a longer RNA strand than when this reaction is conducted at room temperature.
There are several important points and assumptions made in this article:
Points:

• The temperature was brought to the eutectic phase, which is a specific temperature range for a given solution of solvent and solutes. The eutectic phase is colder than the freezing point of the solvent itself, so in this reaction the solution of solute particles and water is brought to below the freezing point of water.


• Bringing the solution to the eutectic point forms an ice-lattice structure that allows for diffusion and compartmentalization of RNA products and side products.


• Ice causes substrate and solute concentration and prevents replicase degradation. It allows for compartmentalization, and certain microstructures of the ice permit diffusion, helping the overall reaction yield. These are very specific results from a specific set of conditions.

Assumptions:

• The authors state that R18 RNA polymerase ribozyme is "the best available modern day analogue of a primordial replicase," which is based on some presuppositions on what the primordial replicase would be. Furthermore, this starting material was purified before use. One of the biggest problems with the RNA-first world is the problem of synthesizing RNA in the first place. The reactions to produce the nucleotides would inhibit the reactions to produce the ribose rings, making the synthesis complicated.


• The cold temperature slows down the reaction, but stabilizes and reduces degradation of replicase product. The authors assume that the slower kinetics is off-set by the stability of the product.


• The authors assume a cold early Earth, or at least cold portions of an early earth. The authors provide references that suggest perhaps the early earth was cold rather than hot; however, this is a contentious issue.


• An assumption that is common in OOL scenarios, from the article: "Our results imply a potentially wider role for ice, promoting all the steps from prebiotic oligomer synthesis to the emergence of RNA self-replication and Darwinian evolution." Thus far, there is no mechanism describing how to move from RNA to a nucleus-like organelle to a protocell to cellular life. This is taken for granted in origin of life scenarios.

While this is a proof-of-concept experiment, some of these assumptions are too specific or troublesome to be ignored.
For example, slowing down an already slow process when the geological clock is ticking is glossed over in this article, but needs to be considered. In these types of reactions, heating speeds the reaction up but risks destroying the products while cooling protects the products, but slows a reaction down (See also Levy and Miller, "The stability of the RNA bases: Implications for the origin of life" Proc. Natl. Acad. Sci USA vol 95:7933(1998).). OOL of life scenarios presume that even though it is highly improbable that some chemicals will randomly come together and form something functional, given enough time, there will be plenty of opportunities (probabilistic chances) for this to happen. If a reaction is slowed down, then there are fewer opportunities for chemicals to meet.
Time is taken for granted, but many scientists content that the opportunity for an origin of life scenario to occur may be in the range of 200-500 million years, short in a geological sense. The actual date of the emergence of life is a contentious issue, but many findings have pushed the date back to the earliest bacteria living 3.5 billion years ago. Furthermore, the early earth's environment was inhospitable for any kind of life or organic chemistry for the first 500 million years (For one example of reports in this field, see Schopf, J. William "The First Billion Years: When Did Life Emerge?" Elements vol 2:229( 2006).). Given the very specific conditions reported in the article and the slower reaction time, there is not enough time (probabilistic chances) for this to be a plausible origin of life scenario.
Finally, this quote from the article gives one pause if one is trying to model a naturalistic origin of life scenario:

Although ice thus more than doubles the primer extension capability of the R18 RNA polymerase ribozyme, significant further improvements are required to bring self-replication of the 195 nucleotide ribozyme within reach. While in-ice RNA replication activity may be enhanced further by continued fine-tuning of solute concentrations and identity, there is no denying that R18, in its current form, is maladapted to the ice phase.

There are many assumptions (too many) that are granted to origin of life scenarios, but the one assumption that should not be granted is "continued fine-tuning," as that negates the entire point of trying to find a naturalistic process that could have produced the earliest protocells and subsequently the earliest forms of life that would continue to evolve. Even given the author's statement that R18 was maladapted to ice, they were using a substance that they had purified, and one that earlier in the article was assumed to be as close to the early earth molecules as possible. The experimental section for this reaction is not a simple mechanism. It has very specific details on how the authors brought the reaction to the right temperature and maintained that temperature, their buffer solution, the effect of particular solute anions on the ice structure, and their work up of the reaction. With every instance of a chemist's intervention (or fine-tuning) to a reaction, one decreases one's probabilistic chances of this reaction occurring by chance.
In any origin of life scenario the problem of the chemists' presence is difficult to ignore. There comes a point when so much tweaking and fine-tuning should tell the experimenter that this reaction is too sensitive to the reaction conditions to be a viable contender in the search for the first reactions that produced life.